SCHEMBL5493471

SCHEMBL5493471

NCCCNC(=O)CCN

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 2/20 0.47
PAOX Q6QHF9 2/20 0.46
CASP2 P42575 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
KDM4A O75164 1/20 0.44
HIF1A Q16665 1/20 0.44
TET2 Q6N021 1/20 0.44
DOHH Q9BU89 1/20 0.44
TSHR P16473 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7211184 0.93 PAOX (0.56) SLC6A5PAOXCASP2L3MBTL1KDM4A
SCHEMBL12829898 0.92 CASP2 (0.46) SLC6A5PAOXCASP2L3MBTL1KDM4A
SCHEMBL7204674 0.92 CASP2 (0.52) SLC6A5PAOXCASP2L3MBTL1KDM4A
SCHEMBL27176325 0.92 SLC6A5 (0.49) SLC6A5PAOXCASP2L3MBTL1KDM4A
SCHEMBL24761185 0.90 SLC6A5 (0.51) SLC6A5PAOXCASP2KDM4AHIF1A
SCHEMBL6745342 0.90 TSHR (0.54) SLC6A5PAOXCASP2KDM4AHIF1A
SCHEMBL6745339 0.90 TSHR (0.54) SLC6A5PAOXCASP2KDM4AHIF1A
SCHEMBL14360491 0.89 PAOX (0.53) PAOXCASP2TSHRCYP2C19MEN1
SCHEMBL9506604 0.88 SLC6A5 (0.59) SLC6A5PAOXKDM4AHIF1ATET2
SCHEMBL27406932 0.86 NAAA (0.59) SLC6A5PAOXCASP2KDM4AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286579-B2 Fire-retardant oriented strand board Arxada, LLC (US) 2025-04-29 US disclosed
US-20220340816-A1 Fire-Retardant Oriented Strand Board Arxada, LLC 2022-10-27 US disclosed
US-11414602-B2 Fire-retardant oriented strand board Arxada, LLC (US) 2022-08-16 US disclosed
US-20210330792-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-10-28 US disclosed
WO-2021125279-A1 CHEMICALLY CROSSLINKED ALGINATE GEL FIBER 持田製薬株式会社 2021-06-24 WO disclosed
US-20200392412-A1 Fire-Retardant Oriented Strand Board LONZA, LLC 2020-12-17 US disclosed
CN-103930108-A (Bacterio)chlorophyll photosensitizers for treatment of eye diseases and disorders YEDA RES & DEV 2014-07-16 CN disclosed
EP-1100816-B1 AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE BASILEA PHARMACEUTICA AG (CH) 2007-08-08 EP disclosed
EP-1251827-B1 NASALLY ADMINISTRABLE ANTIFUNGAL CYCLIC PEPTIDE COMPOSITIONS BASILEA PHARMACEUTICA AG (CH) 2004-05-26 EP disclosed
US-6489440-B1 Cyclic compounds BASILEA PHARMACEUTICA AG (CH) 2002-12-03 US disclosed
EP-1251827-A2 NASALLY ADMINISTRABLE CYCLIC PEPTIDE COMPOSITIONS Basilea Pharmaceutica AG (CH) 2002-10-30 EP disclosed
US-20010038824-A1 Intranasal cyclic peptide formulations BASILEA PHARMACEUTICA AG (CH) 2001-11-08 US disclosed
WO-2001052894-A2 NASALLY ADMINISTRABLE CYCLIC PEPTIDE COMPOSITIONS BASILEA PHARMACEUTICA AG (CH) 2001-07-26 WO disclosed
EP-1100816-A1 AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE F. HOFFMANN-LA ROCHE AG (CH) 2001-05-23 EP disclosed
WO-2000005251-A1 AEROTHRICIN ANALOGS, THEIR PREPARATION AND USE F. HOFFMANN-LA ROCHE AG (CH) 2000-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210330792-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS PPOX, PPIB, PPIA SLC6A5 1596/4885PAOX 66/4885CASP2 3070/4885
US-20010038824-A1 Intranasal cyclic peptide formulations VIP, NPPA, SSTR5 SLC6A5 868/4885PAOX 1895/4885CASP2 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.