Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799968 | 0.74 | OPRK1 (0.38) | KDM4ESLC6A2HTTKMT2AMAPT | |
| SCHEMBL18106120 | 0.69 | PARP1 (0.50) | KDM4ECYP1A2PARP1CYP2D6CYP2C9 | |
| SCHEMBL1986163 | 0.68 | GPR3 (0.39) | KDM4ECYP1A2PARP1SLC6A2HTT | |
| SCHEMBL1715320 | 0.68 | CCR1 (0.61) | KDM4ECYP1A2PARP1CYP2D6CYP2C9 | |
| SCHEMBL659910 | 0.67 | ACHE (0.40) | KDM4ECYP1A2PARP1CYP2D6CYP2C9 | |
| SCHEMBL4303286 | 0.67 | CCR1 (0.59) | KDM4ECYP1A2PARP1CYP2D6CYP2C9 | |
| SCHEMBL4310097 | 0.67 | CCR1 (0.59) | KDM4ECYP1A2PARP1CYP2D6CYP2C9 | |
| SCHEMBL13313366 | 0.67 | CYP1A2 (0.64) | KDM4ECYP1A2PARP1CYP2D6CYP2C9 | |
| SCHEMBL4296866 | 0.67 | CCR1 (0.59) | KDM4ECYP1A2PARP1CYP2D6CYP2C9 | |
| SCHEMBL30284810 | 0.67 | CCR1 (0.59) | KDM4ECYP1A2PARP1CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040263952-A1 | Bridged polysesquioxane host matrices containing lanthanides chelated by organic guest ligands, and methods of making such matrices | LUCENT TECHNOLOGIES, INC. (US) | 2004-12-30 | — | — | US | disclosed |