Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 17/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6726057 | 0.86 | TGFBR1 (0.48) | TGFBR1ALOX5APFEN1 | |
| SCHEMBL6840807 | 0.84 | TGFBR1 (0.45) | TGFBR1CA1CA2 | |
| SCHEMBL6747196 | 0.84 | CA1 (0.43) | TGFBR1CA1CA2ALOX5APFEN1 | |
| SCHEMBL6749607 | 0.82 | SCN9A (0.40) | TGFBR1CA1CA2ALOX5APFEN1 | |
| SCHEMBL6743007 | 0.81 | FEN1 (0.41) | TGFBR1CA1CA2ALOX5APFEN1 | |
| SCHEMBL6746652 | 0.81 | CA1 (0.40) | TGFBR1CA1CA2ALOX5APFEN1 | |
| SCHEMBL6744788 | 0.81 | PTGS2 (0.48) | TGFBR1CA1CA2ALOX5APFEN1 | |
| SCHEMBL6750007 | 0.81 | TGFBR1 (0.42) | TGFBR1CYP2A6CA1CA2ALOX5AP | |
| SCHEMBL6837996 | 0.81 | CA1 (0.47) | TGFBR1CA1CA2 | |
| SCHEMBL7040769 | 0.81 | TGFBR1 (0.47) | TGFBR1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |