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SCHEMBL6746677

SCHEMBL6746677

CCc1ccc(N(c2ccc(CC)cc2)c2ccc(N(c3ccc(CC)cc3)c3ccc([Si](C)(C)OC)cc3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LPL P06858 1/20 0.35
▸ LIPG Q9Y5X9 1/20 0.35
▸ FAAH O00519 1/20 0.35
▸ MGLL Q99685 1/20 0.35
▸ TDP1 Q9NUW8 3/20 0.33
▸ TP53 P04637 2/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ TUBB1 Q9H4B7 2/20 0.33
▸ TSHR P16473 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ EGFR P00533 1/20 0.33
▸ TUBB4A P04350 1/20 0.33
▸ TUBB P07437 1/20 0.33
▸ PDGFRB P09619 1/20 0.33
▸ TUBA3C P0DPH7 1/20 0.33
▸ KDR P35968 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6751417 0.95 NISCH (0.36) LPLLIPGFAAHMGLLTDP1
SCHEMBL3482479 0.90 TP53 (0.39) LPLLIPGTDP1TP53L3MBTL1
SCHEMBL6850681 0.85 LPL (0.35) LPLLIPGFAAHMGLLTDP1
SCHEMBL6846354 0.84 TP53 (0.35) LPLLIPGFAAHMGLLTDP1
SCHEMBL6749551 0.83 LPL (0.36) LPLLIPGFAAHMGLLTDP1
SCHEMBL6749673 0.81 ALDH1A1 (0.43) FAAHMGLLTDP1L3MBTL1MAPK1
SCHEMBL6751519 0.81 ALDH1A1 (0.38) TDP1TSHRALDH1A1NPC1RAB9A
SCHEMBL6744616 0.81 ALDH1A1 (0.38) TDP1TSHRALDH1A1NPC1RAB9A
SCHEMBL6749382 0.81 ALDH1A1 (0.43) FAAHMGLLTDP1L3MBTL1MAPK1
SCHEMBL6849267 0.81 NISCH (0.36) LPLLIPGFAAHMGLLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696588-B2 OXIDATION POTENTIAL OF .3-1.5 V ON THE BASIS OF A STANDARD HYDROGEN ELECTRODE, ALKOXY AND AROMATIC AMINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-02-24 — — US disclosed
EP-0861845-B1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL CO (JP) 2003-05-28 — — EP disclosed
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-08-22 — — US disclosed
US-6369258-B1 SILICON COMPOUND WITH OXIDATION POTENTIAL ON HYDROGEN ELECTRODE POTENTIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-09 — — US disclosed
EP-0861845-A2 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same EPCAM, PIEZO1, OR10J3 LPL 4380/4885LIPG 3728/4885FAAH 4340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.