Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746127 | 0.81 | HTT (0.34) | — | |
| SCHEMBL6744637 | 0.78 | TYK2 (0.33) | GLAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL6744532 | 0.76 | CCR1 (0.35) | NR1H2NR1H3 | |
| SCHEMBL6732768 | 0.76 | GLA (0.32) | NR1H2NR1H3GLATYK2 | |
| SCHEMBL6735150 | 0.75 | PTGS2 (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6728564 | 0.75 | PTGS2 (0.38) | GLAGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL6749846 | 0.75 | PTGS2 (0.36) | NR1H2NR1H3 | |
| SCHEMBL6736724 | 0.74 | PTGS2 (0.36) | GLAGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL6749801 | 0.74 | NR1H2 (0.37) | NR1H2NR1H3 | |
| SCHEMBL6743170 | 0.74 | PTGS2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |