Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | BPTF | Q12830 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16217906 | 0.82 | KMO (0.54) | KMOMIFASIC3BACE1CYP1A2 | |
| SCHEMBL27892301 | 0.81 | KMO (0.49) | KMOMIFASIC3BACE1CYP1A2 | |
| SCHEMBL24774283 | 0.77 | CCNT1 (0.36) | KMOASIC3CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL24773661 | 0.77 | KMO (0.41) | KMO | |
| SCHEMBL284286 | 0.76 | ASIC3 (0.71) | KMOMIFASIC3CYP1A2CYP2C19 | |
| SCHEMBL9627581 | 0.76 | LMNA (0.33) | SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL29406194 | 0.74 | ASIC3 (0.68) | KMOMIFASIC3CYP1A2CYP2C19 | |
| SCHEMBL27904874 | 0.74 | ASIC3 (0.68) | KMOMIFASIC3CYP1A2CYP2C19 | |
| SCHEMBL28218682 | 0.74 | ASIC3 (0.68) | KMOMIFASIC3CYP1A2CYP2C19 | |
| SCHEMBL5700203 | 0.73 | PLAU (0.41) | CYP1A2CYP2C19CYP2C9CYP3A4BPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777412-B2 | PYRIMIDIN-4-YLOXY)PHENYL)-3-METHOXYPROPENOATE DERIVATIVES | SYNGENTA LIMITED (GB) | 2004-08-17 | — | — | US | disclosed |
| US-20040092746-A1 | Pyrimidinyloxyphenyl-3-alkoxypropenoate derivatives as pesticides | CLOUGH JOHN MARTIN (GB) | 2004-05-13 | — | — | US | disclosed |
| US-6613773-B2 | Pyrimidinyloxyphenyl-3-alkoxypropenoates derivatives | SYNGENTA LIMITED (GB) | 2003-09-02 | — | — | US | disclosed |
| US-20030060626-A1 | Fungicides | SYNGENTA LIMITED (GB) | 2003-03-27 | — | — | US | disclosed |
| CN-1036519-C | Fungicides | ICI PLC (GB) | 1997-11-26 | — | — | CN | disclosed |
| EP-0468695-B1 | Fungicides | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| CN-1060289-A | Mycocide | ICI PLC (GB) | 1992-04-15 | — | — | CN | disclosed |
| EP-0468695-A1 | Fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092746-A1 | Pyrimidinyloxyphenyl-3-alkoxypropenoate derivatives as pesticides | DDT, SQOR, TH | KMO 37/4885MIF 4028/4885ASIC3 972/4885 |
| US-20030060626-A1 | Fungicides | CYP51A1, CYP1A1, CYP1A2 | KMO 215/4885MIF 3360/4885ASIC3 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.