Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863037 | 0.86 | KMT2A (0.61) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL1860751 | 0.84 | KMT2A (0.52) | KMT2AMEN1GAAL3MBTL1HDAC1 | |
| SCHEMBL4621924 | 0.80 | ALDH1A1 (0.59) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL1857784 | 0.78 | VDR (0.50) | KMT2AMEN1GAAL3MBTL1MAPT | |
| SCHEMBL1859277 | 0.77 | KMT2A (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6850492 | 0.75 | HDAC1 (0.50) | KMT2AMEN1GAAL3MBTL1HDAC1 | |
| SCHEMBL6852970 | 0.75 | KMT2A (0.49) | KMT2AMEN1GAAL3MBTL1HDAC1 | |
| SCHEMBL9977532 | 0.74 | HTR6 (0.50) | KMT2AMEN1GAAL3MBTL1HDAC1 | |
| SCHEMBL4870762 | 0.73 | KMT2A (0.61) | KMT2AMEN1GAAL3MBTL1LMNA | |
| SCHEMBL7359654 | 0.73 | PRMT5 (0.57) | KMT2AMEN1L3MBTL1HDAC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058720-A2 | COMPOUND LIBRARIES OF 1,3,5-SUBSTITUTE INDAZOLE DERIVATIVES AS COMPOUNDS FOR TARGETTING COMPOUNDS CAPABLE OF BINDING TO THE G-PROTEIN COUPLED RECEPTOR | BIOFOCUS PLC (GB) | 2004-07-15 | — | — | WO | disclosed |