Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7177405 | 0.91 | — | — | |
| SCHEMBL8308963 | 0.69 | DPP4 (0.43) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL8813179 | 0.67 | SLC6A4 (0.45) | KMT2AMEN1RAB9ANPC1FEN1 | |
| SCHEMBL9019946 | 0.67 | TAS1R3 (0.42) | — | |
| SCHEMBL9019967 | 0.67 | TAS1R3 (0.36) | — | |
| SCHEMBL7705486 | 0.66 | GSK3B (0.56) | KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL9237893 | 0.64 | MAPT (0.34) | HPGDKMT2AMEN1MAPTFEN1 | |
| SCHEMBL19806639 | 0.64 | ERCC5 (0.55) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL8100211 | 0.64 | ATM (0.51) | HPGDKMT2AALDH1A1 | |
| SCHEMBL8491762 | 0.64 | ERCC5 (0.45) | KMT2AMEN1FEN1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696613-B2 | REACTING NITROHALOBENZENE DERIVATIVE WITH NITROETHANE IN PRESENCE OF A BASE SELECTED FROM THE GROUP CONSISTING OF A HYDROXIDE, A CARBONATE, A HYDRIDE, AN ALKOXIDE OF AN ALKALI OR ALKALINE EARTH METAL, AND GUANIDINE AND SOLVENT | RHONE POULENC AGROCHIMIE (FR) | 2004-02-24 | — | — | US | disclosed |
| US-6525225-B2 | Reacting a nitro-substituted acetophenone with (1) a mercaptan to replace the nitro group with an alkyl- or phenyl-thio group; or (2) nitroethane to replace the acetyl group with a 1-nitroethyl group | RHONE POULENC AGROCHIMIE (FR) | 2003-02-25 | — | — | US | disclosed |
| US-20020062045-A1 | Process for preparing diketone compounds and precursors thereto | PEVERE VIRGINIE (FR) | 2002-05-23 | — | — | US | disclosed |
| EP-0880498-B1 | PROCESS FOR PREPARING DIKETONE COMPOUNDS | AVENTIS CROPSCIENCE SA (FR) | 2001-11-21 | — | — | EP | disclosed |
| US-20010014761-A1 | Process for preparing diketone compounds and precursors thereto | PEVERE VIRGINIE (FR) | 2001-08-16 | — | — | US | disclosed |
| US-6235942-B1 | REACTION OF KETONE WITH CYCLOPROPANECARBOXYLIC ESTER TO FORM DIKETONE | RHONE-POULENC AGROCHIMIE (FR) | 2001-05-22 | — | — | US | disclosed |
| EP-0880498-A2 | PROCESS FOR PREPARING DIKETONE COMPOUNDS | RHONE-POULENC AGROCHIMIE (FR) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028122-A2 | PROCESS FOR PREPARING DIKETONE COMPOUNDS | RHONE-POULENC AGROCHIMIE (FR) | 1997-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010014761-A1 | Process for preparing diketone compounds and precursors thereto | KMO, DHCR7, KHK | HPGD 3133/4885KMT2A 772/4885MEN1 3767/4885 |
| US-20020062045-A1 | Process for preparing diketone compounds and precursors thereto | KMO, DHCR7, KHK | HPGD 3133/4885KMT2A 772/4885MEN1 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.