Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719823 | 0.87 | LDHA (0.59) | MEN1KMT2AMAPTKDM4ELDHA | |
| SCHEMBL161966 | 0.85 | KDM4E (0.49) | WDR5MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6844201 | 0.84 | KDM4E (0.48) | WDR5MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6464894 | 0.83 | PLK1 (0.66) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL158637 | 0.81 | KDM4E (0.46) | WDR5MEN1KMT2AMAPTKDM4E | |
| SCHEMBL10289511 | 0.79 | CXCR2 (0.53) | WDR5KDM4ELDHAPLK1 | |
| SCHEMBL6746769 | 0.77 | WDR5 (0.56) | WDR5MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6748722 | 0.76 | MAPT (0.61) | MEN1KMT2AMAPTKDM4EPOLB | |
| SCHEMBL5231005 | 0.75 | TAS1R3 (0.53) | MEN1KMT2AKDM4EPOLBMAOA | |
| SCHEMBL13958742 | 0.75 | MAOA (0.41) | MEN1KMT2AKDM4EPOLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092729-B1 | POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM | MITSUI CHEMICALS INC (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-6703459-B1 | ORGANIC TRANSITION METAL COMPLEXES HAVING SPECIFIC STRUCTURE, WHICH CAN FORM COPOLYMERS HAVING LINKAGE FORMED BY MIGRATION OF ACTIVE HYDROGEN OF UNSATURATED MONOMER | MITSUI CHEMICALS, INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| EP-1092729-A1 | POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM | Mitsui Chemicals, Inc. (JP) | 2001-04-18 | — | — | EP | disclosed |