Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5354549 | 0.98 | MAPT (0.56) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5391533 | 0.97 | MAPT (0.59) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL6743986 | 0.93 | ALOX15 (0.64) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5350629 | 0.91 | ALOX15 (0.62) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL5345900 | 0.89 | ALOX15 (0.60) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL10114942 | 0.81 | CHRNA7 (0.85) | KMT2AALOX15HSD17B10MEN1POLB | |
| SCHEMBL6151460 | 0.80 | ADRB1 (0.50) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| Iodide SCHEMBL404487 | 0.80 | MEN1 (0.85) | KMT2AALOX15HSD17B10MEN1POLB | |
| SCHEMBL6746057 | 0.79 | GAA (0.54) | MAPTKMT2AGAAALDH1A1ALOX15 | |
| SCHEMBL17151179 | 0.78 | CYP3A4 (0.51) | KMT2AALOX15HSD17B10MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462091-A1 | Composition for dyeing of keratinic fibers comprising a cationic derivative of p-phenylenediamine substituted by a diazacyclohexane or a diazacyloheptane | L'OREAL (FR) | 2004-09-29 | — | — | EP | claimed |
| US-7186277-B2 | Composition for dyeing keratin fibres, comprising a cationic para-phenylenediamine derivative substituted with a diazacyclohexane or diazacycloheptane ring | L'OREAL SA (FR) | 2007-03-06 | — | — | US | disclosed |
| EP-1462091-A1 | Composition for dyeing of keratinic fibers comprising a cationic derivative of p-phenylenediamine substituted by a diazacyclohexane or a diazacyloheptane | L'OREAL (FR) | 2004-09-29 | — | — | EP | disclosed |