Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.64 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.64 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | GFER | P55789 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5350629 | 0.98 | ALOX15 (0.62) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| Hydrochloric Acid SCHEMBL5345900 | 0.96 | ALOX15 (0.60) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| SCHEMBL6748684 | 0.93 | MAPT (0.58) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| Hydrochloric Acid SCHEMBL5354549 | 0.91 | MAPT (0.56) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| Hydrochloric Acid SCHEMBL5391533 | 0.89 | MAPT (0.59) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| SCHEMBL6151460 | 0.87 | ADRB1 (0.50) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| SCHEMBL6744524 | 0.81 | CHRNA10 (0.56) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| Hydrochloric Acid SCHEMBL5350248 | 0.80 | CHRNA10 (0.55) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| SCHEMBL23347931 | 0.79 | MAPT (0.77) | ALOX15HSD17B10MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL6151120 | 0.79 | MAPT (0.77) | ALOX15HSD17B10MAPK1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462091-A1 | Composition for dyeing of keratinic fibers comprising a cationic derivative of p-phenylenediamine substituted by a diazacyclohexane or a diazacyloheptane | L'OREAL (FR) | 2004-09-29 | — | — | EP | claimed |
| US-7186277-B2 | Composition for dyeing keratin fibres, comprising a cationic para-phenylenediamine derivative substituted with a diazacyclohexane or diazacycloheptane ring | L'OREAL SA (FR) | 2007-03-06 | — | — | US | disclosed |
| EP-1462091-A1 | Composition for dyeing of keratinic fibers comprising a cationic derivative of p-phenylenediamine substituted by a diazacyclohexane or a diazacyloheptane | L'OREAL (FR) | 2004-09-29 | — | — | EP | disclosed |