Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.46 |
| ▸ | HTR3B | O95264 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743986 | 0.87 | ALOX15 (0.64) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| Hydrochloric Acid SCHEMBL5350629 | 0.85 | ALOX15 (0.62) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| Hydrochloric Acid SCHEMBL5345900 | 0.83 | ALOX15 (0.60) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 | |
| SCHEMBL531923 | 0.83 | ADRB1 (0.63) | ADRB1ALOX15HSD17B10MAPK1KMT2A | |
| SCHEMBL6151182 | 0.81 | ADRB1 (0.61) | ADRB1ALOX15HSD17B10MAPK1KMT2A | |
| SCHEMBL12832086 | 0.81 | ADRB1 (0.61) | ADRB1ALOX15HSD17B10MAPK1KMT2A | |
| SCHEMBL6151619 | 0.81 | ADRB1 (0.61) | ADRB1ALOX15HSD17B10MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL3236795 | 0.81 | ALDH1A1 (0.63) | ADRB1ALOX15HSD17B10MAPK1KMT2A | |
| Piperazine SCHEMBL28708983 | 0.81 | ADRB1 (0.61) | ADRB1ALOX15HSD17B10MAPK1KMT2A | |
| SCHEMBL6748684 | 0.80 | MAPT (0.58) | ALOX15HSD17B10MAPK1CYP3A4CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1518860-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogene atoms by a 4-aminophenyle group for dyeing keratinic fibres | L'OREAL (FR) | 2005-03-30 | — | — | EP | claimed |