Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GPX4 | P36969 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6748724 | 0.96 | POLQ (0.40) | POLQHTTMEN1KMT2ATSHR | |
| SCHEMBL6748618 | 0.87 | HTT (0.36) | POLQHTTMEN1KMT2ATSHR | |
| SCHEMBL6858713 | 0.87 | HTT (0.36) | POLQHTTMEN1KMT2ATSHR | |
| SCHEMBL6751508 | 0.87 | POLQ (0.32) | POLQHTTMEN1KMT2ATSHR | |
| SCHEMBL6749487 | 0.87 | CNR2 (0.31) | — | |
| SCHEMBL6746770 | 0.86 | HCRTR2 (0.32) | POLQHTTMEN1KMT2ATSHR | |
| SCHEMBL6744726 | 0.85 | HSD17B1 (0.38) | POLQHTTMEN1KMT2ATSHR | |
| SCHEMBL6748607 | 0.85 | CYP2C19 (0.37) | MEN1KMT2ALTB4R2NPC1ALDH1A1 | |
| SCHEMBL6746686 | 0.85 | CYP2C19 (0.37) | MEN1KMT2ALTB4R2NPC1ALDH1A1 | |
| SCHEMBL6744754 | 0.85 | CYP2C19 (0.37) | MEN1KMT2ALTB4R2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696588-B2 | OXIDATION POTENTIAL OF .3-1.5 V ON THE BASIS OF A STANDARD HYDROGEN ELECTRODE, ALKOXY AND AROMATIC AMINE DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-02-24 | — | — | US | disclosed |
| EP-0861845-B1 | Silicon-containing compound and organic electroluminescence device using the same | SUMITOMO CHEMICAL CO (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-20020115877-A1 | Silicon-containing compound and organic electroluminescence device using the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2002-08-22 | — | — | US | disclosed |
| US-6369258-B1 | SILICON COMPOUND WITH OXIDATION POTENTIAL ON HYDROGEN ELECTRODE POTENTIAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-0861845-A2 | Silicon-containing compound and organic electroluminescence device using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115877-A1 | Silicon-containing compound and organic electroluminescence device using the same | EPCAM, PIEZO1, OR10J3 | POLQ 2213/4885HTT 3465/4885MEN1 3062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.