Sugi Predict

Sugi Predict / Compounds / SCHEMBL6858713

SCHEMBL6858713

SCHEMBL6858713

CCO[Si](C)(OCC)c1ccc(N(c2ccc(-c3ccc(N(c4cccc(C)c4)c4cccc(C)c4)cc3)cc2)c2cccc(C)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 3/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ TSHR P16473 1/20 0.36
▸ HSD17B1 P14061 1/20 0.35
▸ HSD17B2 P37059 1/20 0.35
▸ POLQ O75417 3/20 0.34
▸ LTB4R2 Q9NPC1 1/20 0.34
▸ LMNA P02545 2/20 0.34
▸ MAPT P10636 4/20 0.33
▸ TP53 P04637 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ NPC1 O15118 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ PAX8 Q06710 2/20 0.33
▸ GPX4 P36969 1/20 0.33
▸ ENPP3 O14638 1/20 0.32
▸ JAK2 O60674 1/20 0.32
▸ NR1I2 O75469 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6853136 0.96 KMT2A (0.38) HTTMEN1KMT2ATSHRPOLQ
SCHEMBL6748618 0.89 HTT (0.36) HTTMEN1KMT2ATSHRHSD17B1
SCHEMBL6748985 0.87 POLQ (0.38) HTTMEN1KMT2ATSHRHSD17B1
SCHEMBL6853453 0.87 CNR2 (0.31) —
SCHEMBL6851969 0.87 ADRA2A (0.32) HTTMEN1KMT2ATSHRLMNA
SCHEMBL6854722 0.86 ALDH1A1 (0.33) HTTMEN1KMT2ATSHRLMNA
SCHEMBL6855263 0.86 ENPP3 (0.38) HTTLMNAMAPTTP53POLB
SCHEMBL6856802 0.86 ENPP3 (0.38) HTTLMNAMAPTTP53POLB
SCHEMBL6851733 0.86 ENPP3 (0.38) HTTLMNAMAPTTP53POLB
SCHEMBL6851656 0.86 HSD17B1 (0.37) HTTMEN1KMT2ATSHRHSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696588-B2 OXIDATION POTENTIAL OF .3-1.5 V ON THE BASIS OF A STANDARD HYDROGEN ELECTRODE, ALKOXY AND AROMATIC AMINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-02-24 — — US disclosed
EP-0861845-B1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL CO (JP) 2003-05-28 — — EP disclosed
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2002-08-22 — — US disclosed
US-6369258-B1 SILICON COMPOUND WITH OXIDATION POTENTIAL ON HYDROGEN ELECTRODE POTENTIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-09 — — US disclosed
EP-0861845-A2 Silicon-containing compound and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115877-A1 Silicon-containing compound and organic electroluminescence device using the same EPCAM, PIEZO1, OR10J3 HTT 3465/4885MEN1 3062/4885KMT2A 591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.