SCHEMBL6749178

SCHEMBL6749178

CCOC(OCC)n1cncn1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 11/20 0.38
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
HSP90AA1 P07900 2/20 0.33
CYP3A4 P08684 2/20 0.33
MAPT P10636 1/20 0.33
CYP11B1 P15538 1/20 0.33
TSHR P16473 1/20 0.33
CYP11B2 P19099 1/20 0.33
CYP2C19 P33261 1/20 0.33
FAAH O00519 1/20 0.33
MGLL Q99685 1/20 0.33
POLB P06746 1/20 0.33
CYP26A1 O43174 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2656737 0.89 CYP19A1 (0.33) CYP19A1KMT2AMEN1CYP26A1
SCHEMBL11202221 0.80 HSP90AA1 (0.38) CYP19A1KMT2AMEN1HSP90AA1CYP3A4
SCHEMBL6999923 0.80 CYP19A1 (0.38) CYP19A1KMT2AMEN1HSP90AA1CYP3A4
SCHEMBL8453886 0.71
SCHEMBL5306513 0.71 FAAH (0.49) CYP19A1KMT2AMEN1HSP90AA1CYP3A4
SCHEMBL502219 0.70 CYP1A2 (0.43) CYP19A1KMT2AMEN1HSP90AA1CYP3A4
SCHEMBL10361017 0.70 ALDH1A1 (0.46) CYP19A1KMT2AMEN1HSP90AA1CYP3A4
SCHEMBL20981285 0.70 CYP19A1 (0.38) CYP19A1KMT2AMEN1HSP90AA1CYP3A4
SCHEMBL15688936 0.70 CYP19A1 (0.38) CYP19A1KMT2AMEN1HSP90AA1CYP3A4
SCHEMBL6470267 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040092737-A1 Benzopiperidine derivatives EISAI CO., LTD. 2004-05-13 US disclosed
US-6518423-B1 These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and EISAI CO., LTD. (JP) 2003-02-11 US disclosed
EP-0934941-A1 BENZOPIPERIDINE DERIVATIVES Eisai Co., Ltd. (JP) 1999-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040092737-A1 Benzopiperidine derivatives HLA-DRB1, HRH1, HRH2 CYP19A1 193/4885KMT2A 3395/4885MEN1 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.