Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | ARNT | P27540 | 2/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747309 | 0.90 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL6746439 | 0.88 | CASP1 (0.39) | PTGS2PTGS1KIF11CASP1 | |
| SCHEMBL6746730 | 0.88 | PTGS2 (0.38) | PTGS2KIF11CASP1 | |
| SCHEMBL6744935 | 0.88 | PTGS2 (0.36) | PTGS2PTGS1KIF11CASP1 | |
| SCHEMBL6743712 | 0.88 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL6743877 | 0.87 | PTGS2 (0.47) | PTGS2PTGS1KIF11CASP1 | |
| SCHEMBL6746753 | 0.86 | PTGS2 (0.45) | PTGS2PTGS1KIF11CASP1 | |
| SCHEMBL6749852 | 0.86 | PTGS2 (0.50) | PTGS2PTGS1CASP1 | |
| SCHEMBL6747363 | 0.85 | PTGS2 (0.33) | PTGS2PTGS1KIF11CASP1 | |
| SCHEMBL6745050 | 0.85 | PTGS2 (0.42) | PTGS2PTGS1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |