Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743877 | 0.91 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL6746730 | 0.90 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL6750004 | 0.90 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL6746746 | 0.88 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL6746211 | 0.88 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL6746358 | 0.85 | KIF11 (0.46) | PTGS2PTGS1 | |
| SCHEMBL6746753 | 0.85 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL6749852 | 0.85 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL6745090 | 0.85 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL6746873 | 0.84 | EPAS1 (0.36) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |