Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465930 | 0.76 | ALOX5 (0.57) | CYP2D6SRCLMNAMAPK1ALOX5 | |
| SCHEMBL28645044 | 0.75 | ALOX5 (0.42) | CYP2D6SRCAOC3ALOX5 | |
| SCHEMBL18586628 | 0.72 | GABBR2 (0.48) | CYP2D6SRCLMNAMAPK1 | |
| SCHEMBL465969 | 0.70 | TDP1 (0.61) | CYP2D6SRCLMNAMAPK1CES2 | |
| SCHEMBL15955097 | 0.70 | ALOX5 (0.65) | LMNAALOX5 | |
| SCHEMBL644556 | 0.70 | CYP2D6 (0.43) | CYP2D6SRCLMNAMAPK1CES2 | |
| Phosphine SCHEMBL28775755 | 0.69 | TDP1 (0.58) | CYP2D6SRCLMNAMAPK1CES2 | |
| SCHEMBL10595560 | 0.69 | SRC (0.46) | CYP2D6SRCLMNAMAPK1AOC3 | |
| SCHEMBL10820763 | 0.69 | CYP2D6 (0.41) | CYP2D6SRCLMNAMAPK1CES2 | |
| SCHEMBL25416134 | 0.68 | TRPM8 (0.54) | CYP2D6LMNAMAPK1AOC3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226272-A2 | DOUBLE-STRAND NUCLEIC ACID PROBES AND THE USE THEREOF | Nanogen Recognomics GmbH (DE) | 2002-07-31 | — | — | EP | claimed |
| WO-2001031057-A2 | DOUBLE-STRAND NUCLEIC ACID PROBES AND THE USE THEREOF | NANOGEN RECOGNOMICS GMBH (DE) | 2001-05-03 | — | — | WO | claimed |
| US-20040170990-A1 | Intracellular nucleic acid inhibitors of small guanine nucleotide exchange factors | WALDEMAR KOLANUS (DE) | 2004-09-02 | — | — | US | disclosed |