SCHEMBL6750487

SCHEMBL6750487

Nc1ccc(Oc2ccc(C3(c4ccc(Oc5ccc(N)cc5)cc4)C=CC(c4ccccc4)=CC3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.45
NCOA1 Q15788 1/20 0.40
NCOA3 Q9Y6Q9 1/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
NLRP3 Q96P20 1/20 0.39
ALDH1A1 P00352 7/20 0.38
MAPT P10636 6/20 0.38
LMNA P02545 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
TDP1 Q9NUW8 3/20 0.38
CYP3A4 P08684 3/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
MITF O75030 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
NLRP1 Q9C000 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7169779 0.92 HSD17B10 (0.39) MAOAMEN1KMT2ANPC1RAB9A
SCHEMBL6709171 0.87 CYP3A4 (0.38) MAOAMEN1KMT2ANPC1RAB9A
SCHEMBL5848845 0.78 OPRM1 (0.44) KMT2ANPC1RAB9AALDH1A1MAPT
SCHEMBL25383769 0.77 HSD17B10 (0.39) MAOAMEN1KMT2ANPC1RAB9A
SCHEMBL1119476 0.76 MAOA (0.37) MAOANCOA1NCOA3MEN1KMT2A
SCHEMBL5852516 0.74 HSD17B10 (0.46) MAOAMEN1KMT2ANPC1RAB9A
SCHEMBL14150217 0.74 NOTUM (0.39) NPC1RAB9AMAPTLMNASMN1; SMN2
SCHEMBL29488303 0.73 ALDH1A1 (0.41) MAOANCOA1NCOA3MEN1KMT2A
SCHEMBL29085726 0.73 MAPT (0.34) MAOAMEN1KMT2ARAB9AALDH1A1
SCHEMBL28339134 0.71 SMN1; SMN2 (0.33) MAOANCOA1NCOA3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6685997-B1 SOLUTION CONTAINING POLYAMIC ACIDS, POLYAMIDES AND POLYIMIDES; ALIGNMENT FILM; WELL BALANCED ELECTRICAL CHARACTERISTICS; ELIMINATES IMAGE STICKING CHISSO CORPORATION (JP) 2004-02-03 US disclosed