SCHEMBL675081

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL674838	0.89	TUBB4A (0.32)	HSP90AA1HSP90AB1LMNATUBB4ATUBB
	SCHEMBL675722	0.89	LMNA (0.35)	LMNAMAPTALDH1A1HPGDNPSR1
	SCHEMBL16782522	0.85	BPTF (0.39)	HSP90AA1HSP90AB1LMNATUBB4ATUBB
	SCHEMBL4595972	0.84	LMNA (0.35)	LMNAMAPTALDH1A1HPGDNPSR1
	SCHEMBL5942615	0.82	POLB (0.34)	ALDH1A1HPGDPOLBCYP3A4PTPN1
	SCHEMBL674871	0.82	ALDH1A1 (0.35)	HSP90AA1HSP90AB1LMNATUBB4ATUBB
	SCHEMBL675367	0.82	MAPT (0.37)	LMNAMAPTALDH1A1HPGDNPSR1
	SCHEMBL6247176	0.81	KMT2A (0.36)	LMNAMAPTALDH1A1HPGDNPSR1
	SCHEMBL675374	0.80	POLB (0.33)	LMNATUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL6246171	0.80	MAPT (0.35)	HSP90AA1HSP90AB1LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.