SCHEMBL674838

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16782522	0.91	BPTF (0.39)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL675081	0.89	HSP90AA1 (0.34)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL676192	0.89	LMNA (0.34)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL675374	0.89	POLB (0.33)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL676223	0.88	ALDH1A1 (0.35)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL29358934	0.86	PTPN1 (0.36)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL526805	0.86	PTPN1 (0.36)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL674954	0.85	ALDH1A1 (0.36)	LMNAMAPTPOLBCYP3A4HPGD
	SCHEMBL5942424	0.83	NNMT (0.33)	POLBCYP3A4HPGDALDH1A1MEN1
	SCHEMBL29351890	0.83	HPGD (0.35)	LMNAMAPTPOLBCYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.