SCHEMBL6750845

SCHEMBL6750845

CCCCCCCCOC(=O)Nc1cc(C(C)(C)C)cc(C(C)(C)C)c1O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.48
NR5A1 Q13285 1/20 0.48
EPHX1 P07099 1/20 0.42
ESR1 P03372 3/20 0.42
AKR1C4 P17516 1/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
AKR1C1 Q04828 1/20 0.42
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27811404 0.89 NR5A2 (0.40) NR5A2NR5A1EPHX1ESR1AKR1C4
SCHEMBL45414 0.82 ALDH1A1 (0.51) EPHX1ESR1AKR1C4AKR1C3AKR1C2
SCHEMBL11803015 0.82 ALDH1A1 (0.51) EPHX1ESR1AKR1C4AKR1C3AKR1C2
SCHEMBL27989659 0.81 NR5A2 (0.46) NR5A2NR5A1ESR1AKR1C4AKR1C3
SCHEMBL8956367 0.80 EPHX1 (0.44) EPHX1ESR1AKR1C4AKR1C3AKR1C2
SCHEMBL6019410 0.80 EPHX1 (0.44) EPHX1ESR1AKR1C4AKR1C3AKR1C2
SCHEMBL18646077 0.80 NR5A2 (0.52) NR5A2NR5A1ALDH1A1L3MBTL1LMNA
SCHEMBL2805607 0.79 NR5A2 (0.57) NR5A2NR5A1ESR1AKR1C4AKR1C3
SCHEMBL5996234 0.79 NR5A2 (0.57) NR5A2NR5A1ESR1AKR1C4AKR1C3
SCHEMBL5564811 0.79 NR5A2 (0.57) NR5A2NR5A1ESR1AKR1C4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105693698-B Multi-functional hindered amine light stabilizer 巴斯夫欧洲公司 2019-11-22 CN disclosed
CN-110446749-A Light stabilizer mixture BASF SE 2019-11-12 CN disclosed
CN-105683313-B Purposes of 2- (2- hydroxyphenyl) benzotriazole cpd in coating as UV absorbent 巴斯夫欧洲公司 2019-09-17 CN disclosed
CN-109642049-A Additive agent mixture 巴斯夫欧洲公司 2019-04-16 CN disclosed
CN-105960432-B Phosphorus-containing 3-phenylbenzofuran-2-one derivatives as stabilizers 巴斯夫欧洲公司 2019-02-15 CN disclosed
CN-103980618-B Single layer and multilayer blown film 巴斯夫欧洲公司 2018-11-13 CN disclosed
CN-105754099-B Composition and polymer 旭化成株式会社 2018-09-18 CN disclosed
CN-105283529-B Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility 巴斯夫欧洲公司 2018-08-10 CN disclosed
CN-105247024-B Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility 巴斯夫欧洲公司 2018-08-10 CN disclosed
CN-107922673-A Phosphorus-containing 3-phenyl-benzofuran-2-one derivatives as stabilizers 巴斯夫欧洲公司 2018-04-17 CN disclosed
CN-102124079-A Thermally insulating films and laminates BASF SE 2011-07-13 CN disclosed
CN-102066451-A Hyperbranched polymers and oligomers containing terminal amino groups as curing agents for epoxy resins BASF SE 2011-05-18 CN disclosed
CN-101189318-A Reversibly thermochromic compositions CIBA SC HOLDING AG (CH) 2008-05-28 CN disclosed
US-20040242437-A1 Antiwear performance of engine oils with $g(b)-dithiophosphorylated propionic acids CIBA SPECIALTY CHEMICALS CORP. 2004-12-02 US disclosed
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2003-06-26 US disclosed
CN-1080283-C Synergic stabilizato mixture CIBA GEIGY (CH) 2002-03-06 CN disclosed
CN-1067994-C Bisresorcinyltriazines CIBA GEIGY AG (CH) 2001-07-04 CN disclosed
CN-1041415-C 3-arylbenzofuranone stabilizers and uses thereof CIBA GEIGY AG (CH) 1998-12-30 CN disclosed
CN-1040208-C 3-(2-acyloxyethoxyphenyl) benzofuran-2-ones for use as stabilizers SPECIALTY CHEMICALS HOLDING IN (CH) 1998-10-14 CN disclosed
CN-1139683-A Synergic stabilizato mixture CIBA GEIGY (CH) 1997-01-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, POLH, OGFOD1 NR5A2 3616/4885NR5A1 3802/4885EPHX1 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.