SCHEMBL6751270

SCHEMBL6751270

CC(=O)CCCCC1SCC2NC(=O)NC21

nearest known ligand 0.77

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.77
▸ MEN1 O00255 1/20 0.77
▸ ABL1 P00519 1/20 0.77
▸ LMNA P02545 1/20 0.77
▸ PKM P14618 1/20 0.77
▸ IDE P14735 1/20 0.77
▸ MAPK1 P28482 1/20 0.77
▸ KMT2A Q03164 1/20 0.77
▸ RIN1 Q13671 1/20 0.77
▸ L3MBTL1 Q9Y468 1/20 0.77
▸ HLCS P50747 6/20 0.69
▸ CA12 O43570 7/20 0.55
▸ CA1 P00915 7/20 0.55
▸ CA2 P00918 7/20 0.55
▸ CA9 Q16790 7/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17348120 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL12852783 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL18413943 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL12060446 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL13380511 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL13563116 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL13525124 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL14594154 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL12119296 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL13525109 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026358-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2024-01-25 — — US disclosed
WO-2023220428-A1 COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-11-16 — — WO disclosed
EP-4276090-A1 CATIONIC LIPID, LIPOSOME CONTAINING CATIONIC LIPID, AND NUCLEIC-ACID PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME AND PREPARATION AND APPLICATION THEREOF Xiamen Sinopeg Biotech Co., Ltd. (CN) 2023-11-15 — — EP disclosed
US-20230220384-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-07-13 — — US disclosed
EP-3022206-B1 EPHA4 INHIBITORS AS NEUROPROTECTIVE AGENTS UNIV HONG KONG SCIENCE & TECH (HK) 2023-07-12 — — EP disclosed
EP-3405477-B1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2023-06-07 — — EP disclosed
WO-2023091644-A2 HSD17B13-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-05-25 — — WO disclosed
WO-2023049218-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-03-30 — — WO disclosed
US-20230048956-A1 BIOTIN MOIETY-CONJUGATED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING THE SAME D&D PHARMATECH INC. (KR) 2023-02-16 — — US disclosed
US-20230000834-A1 PHYSIOLOGICALLY ACTIVE SUBSTANCE BOUND TO BIOTIN MOIETY, AND COMPOSITION FOR ORAL ADMINISTRATION INCLUDING SAME D&D PHARMATECH, INC. (KP) 2023-01-05 — — US disclosed
EP-1813946-A1 BIOMATERIAL CONSTRUCT, ITS PRODUCING METHOD, BIOMATERIAL SUPPORT, TARGET MATERIAL PURIFYING METHOD, AFFINITY CHROMATOGRAPHY CONTAINER, SEPARATION CHIP, ANALYZING METHOD AND ANALYZING SEPARATOR FOR TARGET MATERIAL, BIOMATERIAL COMPLEX, AND ITS SUPPORT, SENSOR CHIP, SOLID SUPPORT WITH BIOMATERIAL FIXE Mitsubishi Chemical Corporation (JP) 2007-08-01 — — EP disclosed
US-20070154894-A1 Labeling and non-enzymatic fragmentation of cDNA using a ribonucleoside triphosphate analog AFFYMETRIX, INC. (US) 2007-07-05 — — US disclosed
US-20070154894-A1 Labeling and non-enzymatic fragmentation of cDNA using a ribonucleoside triphosphate analog AFFYMETRIX, INC. (US) 2007-07-05 — — US disclosed
US-20070149446-A1 Tamandarin analogs and fragments thereof and methods of making and using THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA CENTER FOR TECHNOLOGY TRANSFER (US) 2007-06-28 — — US disclosed
US-20070141624-A1 ACTIVITY-BASED PROBES AND METHODS OF THEIR PREPARATION ANS USE ACTIVX BIOSCIENCES, INC. 2007-06-21 — — US disclosed
US-7220847-B2 Detectable labeled nucleoside analogs and methods of use thereof ROCHE MOLECULAR SYSTEMS, INC. (US) 2007-05-22 — — US disclosed
US-7220847-B2 Detectable labeled nucleoside analogs and methods of use thereof ROCHE MOLECULAR SYSTEMS, INC. (US) 2007-05-22 — — US disclosed
US-20070087361-A1 Solid support assay systems and methods utilizing non-standard bases ERAGEN BIOSCIENCES, INC. 2007-04-19 — — US disclosed
WO-2007038172-A2 GUANIDINIUM CARRIERS NITTO DENKO CORPORATION (JP) 2007-04-05 — — WO disclosed
US-20070078094-A1 Guanidinium delivery carriers NITTO DENKO CORPORATION (JP) 2007-04-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070141624-A1 ACTIVITY-BASED PROBES AND METHODS OF THEIR PREPARATION ANS USE DNPEP, CTRL, ARSA TDP1 664/4885MEN1 4670/4885ABL1 710/4885
US-20070078094-A1 Guanidinium delivery carriers SLC2A9, SLC29A2, SLC2A4 TDP1 1606/4885MEN1 3995/4885ABL1 3517/4885
US-20230000834-A1 PHYSIOLOGICALLY ACTIVE SUBSTANCE BOUND TO BIOTIN MOIETY, AND COMPOSITION FOR ORAL ADMINISTRATION INCLUDING SAME BTD, FABP2, PLPBP TDP1 4587/4885MEN1 1379/4885ABL1 4705/4885
US-20070154894-A1 Labeling and non-enzymatic fragmentation of cDNA using a ribonucleoside triphosphate analog RNGTT, POLRMT, BTD TDP1 287/4885MEN1 4185/4885ABL1 4326/4885
US-20230048956-A1 BIOTIN MOIETY-CONJUGATED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION COMPRISING THE SAME VIP, BTD, HLCS TDP1 4789/4885MEN1 1487/4885ABL1 3647/4885
US-20070149446-A1 Tamandarin analogs and fragments thereof and methods of making and using FOXM1, F3, RB1 TDP1 3098/4885MEN1 493/4885ABL1 1018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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