Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 4/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751117 | 0.86 | JAK2 (0.48) | ALDH1A1KCNK3KCNK9GRIA1TP53 | |
| SCHEMBL4726455 | 0.83 | HSD11B1 (0.41) | MAPK14KDM4EALDH1A1CNR2HTR2B | |
| SCHEMBL6752291 | 0.82 | RORC (0.43) | BTKKCNK3KCNK9HTR2BHSD11B1 | |
| SCHEMBL6039857 | 0.79 | TNK2 (0.46) | KCNH2MAPK11MAPK14KDM4EALDH1A1 | |
| SCHEMBL6040019 | 0.79 | OPRM1 (0.41) | KCNH2MAPK14KDM4EALDH1A1HPGD | |
| SCHEMBL6848068 | 0.78 | EPHX2 (0.55) | KCNK3KCNK9 | |
| SCHEMBL6039497 | 0.77 | PRCP (0.52) | — | |
| SCHEMBL6039873 | 0.77 | HPGDS (0.51) | KDM4EALDH1A1CNR2 | |
| SCHEMBL7170296 | 0.76 | BTK (0.47) | BTKKCNK3KCNK9 | |
| SCHEMBL7170299 | 0.76 | BTK (0.47) | BTKKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058755-A2 | COMPOUND LIBRARIES OF IMIDAZO[1,5-A]PYRIDIN-3-YL DERIVATIVES AND RELATED HETEROBICYCLES FOR TARGETTING COMPOUNDS CAPABLE OF BINDING TO G-PROTEIN COUPLED RECEPTORS | BIOFOCUS PLC (GB) | 2004-07-15 | — | — | WO | disclosed |