Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126493 | 0.77 | CYP1A2 (0.44) | SMN1; SMN2CYP1A2TDP1CYP2C19KDM4E | |
| SCHEMBL11355863 | 0.73 | RAB9A (0.45) | SMN1; SMN2CYP1A2TDP1CYP2C19KDM4E | |
| SCHEMBL7246198 | 0.72 | PAM (0.41) | SMN1; SMN2CYP1A2TDP1CYP2C19MEN1 | |
| SCHEMBL11355072 | 0.70 | ANPEP (0.43) | SMN1; SMN2CYP1A2TDP1CYP2C19KDM4E | |
| SCHEMBL6749918 | 0.68 | EPHX1 (0.69) | SMN1; SMN2KDM4EALDH1A1HPGDGAA | |
| SCHEMBL11214374 | 0.66 | ANPEP (0.46) | SMN1; SMN2CYP1A2TDP1CYP2C19KDM4E | |
| SCHEMBL28342424 | 0.65 | CYP1A2 (0.42) | SMN1; SMN2CYP1A2TDP1CYP2C19KDM4E | |
| SCHEMBL7187363 | 0.65 | MTNR1A (0.42) | SMN1; SMN2CYP1A2KDM4EALDH1A1MAPT | |
| SCHEMBL24214293 | 0.64 | ALDH1A1 (0.47) | TDP1ALDH1A1KMT2ACYP3A4TSHR | |
| SCHEMBL6910507 | 0.64 | ANPEP (0.44) | SMN1; SMN2CYP1A2TDP1CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710200-B2 | USING REPORTER MOLECULE DERIVATIVE HAVING ALDEHYDE OR KETONE GROUP DETECTABLE BY FLUORESCENCE EMISSION, ULTRAVIOLET RADIATION, ABSORPTIVITY OR COLORIMETRIC ANALYSIS; REARRANGEMENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-03-23 | — | — | US | disclosed |