SCHEMBL4322359

SCHEMBL4322359

COc1ccc2c(c1)c(CC(=O)OCCl)c(C)n2C(=O)c1ccccc1Cl

nearest known ligand 0.85

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.85
CNR1 P21554 5/20 0.85
PTGS2 P35354 10/20 0.63
HIF1A Q16665 2/20 0.60
HTR1A P08908 1/20 0.60
PKM P14618 1/20 0.60
PTGS1 P23219 1/20 0.60
GLO1 Q04760 1/20 0.60
AKR1C3 P42330 2/20 0.60
LMNA P02545 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
TSHR P16473 1/20 0.59
NFKB1 P19838 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6753402 0.89 CNR1 (0.83) CNR2CNR1PTGS2HIF1AHTR1A
SCHEMBL12988768 0.85 PTGS2 (0.86) CNR2PTGS2HIF1AHTR1APKM
SCHEMBL29855593 0.85 PTGS2 (0.86) CNR2PTGS2HIF1AHTR1APKM
SCHEMBL8932650 0.81 CNR2 (1.00) CNR2CNR1PTGS2HIF1APKM
SCHEMBL8932634 0.81 CNR2 (0.88) CNR2CNR1PTGS2PKMCYP1A2
SCHEMBL5801098 0.81 CNR1 (0.73) CNR2CNR1PTGS2HIF1APTGS1
SCHEMBL11149891 0.79 PTGS2 (0.76) CNR2PTGS2HIF1AHTR1APKM
SCHEMBL29355098 0.79 PTGS2 (0.82) CNR2PTGS2HIF1AHTR1APKM
SCHEMBL10518353 0.78 PTGS2 (0.69) CNR2CNR1PTGS2HIF1AHTR1A
SCHEMBL4549122 0.78 PTGS2 (1.00) CNR2PTGS2HIF1AHTR1APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118330991-A Composition for forming resist underlayer film, pattern forming method, and method for forming resist underlayer film 信越化学工业株式会社 2024-07-12 CN disclosed
US-20240019782-A1 Composition For Forming Metal Oxide Film, Patterning Process, And Method For Forming Metal Oxide Film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-18 US disclosed
EP-4303657-A2 COMPOSITION FOR FORMING METAL OXIDE FILM, PATTERNING PROCESS, AND METHOD FOR FORMING METAL OXIDE FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-10 EP disclosed
CN-117363058-A Composition for forming metal oxide film, pattern forming method, and metal oxide film forming method 信越化学工业株式会社 2024-01-09 CN disclosed
CN-117024997-A Composition for forming metal oxide film, pattern forming method, and metal oxide film forming method 信越化学工业株式会社 2023-11-10 CN disclosed
CN-116661242-A Planarization agent for forming organic film, composition for forming organic film, method for forming organic film, and method for forming pattern 信越化学工业株式会社 2023-08-29 CN disclosed
CN-104725620-A Unsaturated polylactic acid segmented copolymer and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2015-06-24 CN disclosed
CN-101616975-B Mixtures of n-alkanols and their use BASF SE 2014-08-06 CN disclosed
CN-101616975-A The mixture of n-alkanols and their purposes BASF SE 2009-12-30 CN disclosed
US-20090186859-A1 DIAZENIUMDIOLATED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, COMPOSITIONS THEREOF, AND RELATED METHODS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SEC., DEPT. OF HEALTH AND HUMAN SERVICES (MD) 2009-07-23 US disclosed
EP-2039718-A2 Quickly coagulating softener preparations Lanxess Deutschland GmbH (DE) 2009-03-25 EP disclosed
EP-2010486-A2 DIAZENIUMDIOLATED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, COMPOSITIONS THEREOF, AND RELATED METHODS The Government Of The United States Of America As Representative National Institutes of Health (US) 2009-01-07 EP disclosed
WO-2007127725-A2 DIAZENIUMDIOLATED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, COMPOSITIONS THEREOF, AND RELATED METHODS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2007-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186859-A1 DIAZENIUMDIOLATED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, COMPOSITIONS THEREOF, AND RELATED METHODS NOS2, NOS1, NOS3 CNR2 230/4885CNR1 337/4885PTGS2 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.