Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3546605 | 0.91 | CCR2 (0.51) | CCR2MAOAMEN1KMT2ASCN9A | |
| SCHEMBL6753593 | 0.81 | CCR2 (0.40) | CCR2MAOASCN9ASSTR3KDM1A | |
| SCHEMBL11929041 | 0.79 | MAPK9 (0.41) | CCR2MEN1KMT2A | |
| SCHEMBL12334073 | 0.77 | CCKBR (0.49) | MEN1KMT2AMAPK14CCKBR | |
| SCHEMBL3545167 | 0.74 | ALDH1A1 (0.50) | CCR2MEN1KMT2A | |
| SCHEMBL3480150 | 0.72 | MAPK9 (0.56) | CCR2MEN1KMT2A | |
| SCHEMBL3546787 | 0.72 | CCR2 (0.48) | CCR2 | |
| SCHEMBL3545198 | 0.72 | CCR2 (0.54) | CCR2KMT2A | |
| SCHEMBL6436632 | 0.72 | MEN1 (0.57) | MEN1KMT2A | |
| SCHEMBL3546609 | 0.71 | MAPK9 (0.42) | CCR2MEN1KMT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409483-A1 | ARYLSULFONAMIDE DERIVATIVES AS C-JUN-N-TERMINAL KINASES (JNK'S) INHIBITORS | Applied Research Systems ARS Holding N.V. (AN) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003010164-A1 | ARYLSULFONAMIDE DERIVATIVES AS C-JUN-N-TERMINAL KINASES (JNK'S) INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-02-06 | — | — | WO | disclosed |