Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3547611 | 0.93 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ACCR2DDR1 | |
| SCHEMBL3545170 | 0.82 | POLB (0.41) | ALDH1A1ACKR3MEN1KMT2APOLB | |
| SCHEMBL3545198 | 0.80 | CCR2 (0.54) | KMT2ACCR2DDR1NPC1 | |
| SCHEMBL3544308 | 0.79 | CCR2 (0.53) | CCR2DDR1 | |
| SCHEMBL3480186 | 0.75 | MAPK9 (0.49) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3546787 | 0.75 | CCR2 (0.48) | CHRM4CCR2DRD4 | |
| SCHEMBL6753597 | 0.74 | CCR2 (0.52) | MEN1KMT2ACCR2 | |
| SCHEMBL12334073 | 0.73 | CCKBR (0.49) | MEN1KMT2ANPC1 | |
| SCHEMBL3479914 | 0.72 | MAPK9 (0.53) | ALDH1A1MEN1KMT2APOLBCCR2 | |
| SCHEMBL3479910 | 0.72 | MAPK9 (0.53) | ALDH1A1MEN1KMT2APOLBCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683078-B2 | Arylsulfonamide derivatives as C-Jun-N-Terminal Kinases (JNK's) inhibitors | LABORATOIRES SERONO S.A. (CH) | 2010-03-23 | — | — | US | claimed |