Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.30 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708767 | 0.90 | HIF1A (0.35) | MAP2K1TP53MAPTS1PR1S1PR3 | |
| SCHEMBL6708933 | 0.86 | LRRK2 (0.38) | LRRK2 | |
| SCHEMBL6833954 | 0.85 | RORC (0.35) | RORCMAP2K1TP53POLBMAPT | |
| SCHEMBL6709124 | 0.81 | LMNA (0.35) | RORCTP53MAPT | |
| SCHEMBL6818600 | 0.80 | TP53 (0.34) | RORCMAP2K1TP53POLBMAPT | |
| SCHEMBL6710378 | 0.79 | SMN1; SMN2 (0.35) | TP53MAPTAR | |
| SCHEMBL6710332 | 0.79 | EPHX2 (0.39) | TP53MAPTRAPGEF3RAPGEF4AR | |
| SCHEMBL6818406 | 0.78 | RORC (0.34) | RORCMAP2K1TP53POLBMAPT | |
| SCHEMBL6819217 | 0.78 | PDE10A (0.37) | RORCMAP2K1TP53POLBMAPT | |
| SCHEMBL6822026 | 0.78 | EGLN2 (0.35) | RORCLRRK2MAP2K1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | RORC 1202/4885LRRK2 4612/4885MAP2K1 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.