Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94758 | 0.98 | MMP1 (0.38) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL27558802 | 0.94 | MMP1 (0.36) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL1168152 | 0.92 | MMP1 (0.42) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL9548469 | 0.87 | TSHR (0.36) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL3749621 | 0.86 | TSHR (0.45) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL1864892 | 0.86 | LMNA (0.42) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL68486 | 0.85 | LMNA (0.45) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL3749627 | 0.83 | MMP1 (0.39) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL14935874 | 0.83 | LMNA (0.39) | TSHRMMP1MMP2MMP3MMP9 | |
| SCHEMBL27860849 | 0.82 | LMNA (0.42) | TSHRMMP1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523956-B2 | Fabric care composition comprising water soluble or water dispersible copolymer containing UV-absorbing monomer | UNILEVER PLC (GB) | 1999-02-03 | — | — | EP | claimed |
| US-5330672-A | Detergents, polyamideester copolymers, sunscreen agents | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1994-07-19 | — | — | US | claimed |
| WO-1993022413-A1 | COMPOSITIONS COMPRISING WATER-DISPERSIBLE COPOLYMER CONTAINING UVA AND UVB LIGHT-ABSORBING MONOMERS | UNILEVER PLC (GB) | 1993-11-11 | — | — | WO | claimed |
| EP-0523956-A2 | Fabric care composition comprising water soluble or water dispersible copolymer containing UV-absorbing monomer | UNILEVER PLC (GB) | 1993-01-20 | — | — | EP | claimed |
| US-5089163-A | Storage stability | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1992-02-18 | — | — | US | claimed |
| US-5082578-A | Fabric care compositions containing a polymeric fluorescent whitening agent | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1992-01-21 | — | — | US | claimed |
| US-6716808-B1 | LAUNDRY DETERGENTS | THE PROCTER & GAMBLE COMPANY | 2004-04-06 | — | — | US | disclosed |
| US-6387873-B1 | MIXTURE OF DETERGENT AND ZEOLITE | THE PROCTER & GAMBLE COMPANY | 2002-05-14 | — | — | US | disclosed |
| EP-0900262-A1 | DETERGENT COMPOSITIONS COMPRISING POLYAMINE SCAVENGER AGENTS AND ENZYMES | THE PROCTER & GAMBLE COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| EP-0523956-B2 | Fabric care composition comprising water soluble or water dispersible copolymer containing UV-absorbing monomer | UNILEVER PLC (GB) | 1999-02-03 | — | — | EP | disclosed |
| US-5700771-A | Polyhydroxy fatty acid amide surfactants in percarbonate bleach-containing compositions | THE PROCTER & GAMBLE COMPANY (US) | 1997-12-23 | — | — | US | disclosed |
| WO-1997042284-A1 | DETERGENT COMPOSITIONS COMPRISING POLYAMINE SCAVENGER AGENTS AND ENZYMES | THE PROCTER & GAMBLE COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |
| EP-0765380-A1 | DYE FADING PROTECTION FROM SOIL RELEASE AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1997-04-02 | — | — | EP | disclosed |
| WO-1992006153-A1 | DETERGENT COMPOSITIONS WITH POLYHYDROXY FATTY ACID AMIDE SURFACTANT AND POLYMERIC DISPERSING AGENT | THE PROCTER & GAMBLE COMPANY (US) | 1992-04-16 | — | — | WO | disclosed |
| US-5082578-A | Fabric care compositions containing a polymeric fluorescent whitening agent | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1992-01-21 | — | — | US | disclosed |
| US-4976879-A | Laundering using a copolyester of 1,2-propylene glycol, ethylene glycol and terephthalic acid endcapped with a salt of a sulfobenzoic acid | THE PROCTER & GAMBLE COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4968451-A | LAUNDRY DETERGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0357280-A2 | Soil release agents having allylderived sulfonated end caps | THE PROCTER & GAMBLE COMPANY (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4877896-A | Sulfoaroyl end-capped ester of oligomers suitable as soil-release agents in detergent compositions and fabric-conditioner articles | THE PROCTER & GAMBLE COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
| EP-0233010-A2 | Detergency builder system | THE PROCTER & GAMBLE COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |