Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18783181 | 0.87 | CYP3A4 (0.50) | NPC1MAPTLMNACYP3A4TSHR | |
| SCHEMBL127127 | 0.85 | NPC1 (0.53) | NPC1RAB9AKMT2AMEN1ESR1 | |
| SCHEMBL6754597 | 0.84 | NPC1 (0.44) | NPC1RAB9AKMT2AMEN1ESR1 | |
| SCHEMBL27979749 | 0.83 | LMNA (0.50) | KMT2AMAPTLMNACYP3A4TSHR | |
| SCHEMBL1254075 | 0.82 | TSHR (0.66) | LMNACYP3A4TSHRALDH1A1TP53 | |
| SCHEMBL17133609 | 0.81 | ALDH1A1 (0.50) | KMT2AMAPTLMNACYP3A4ALDH1A1 | |
| SCHEMBL7633538 | 0.80 | NPC1 (0.46) | NPC1RAB9AKMT2AMEN1ESR1 | |
| SCHEMBL15946442 | 0.79 | THRB (0.54) | KMT2AMEN1LMNACYP3A4TSHR | |
| SCHEMBL1249886 | 0.78 | TSHR (0.46) | NPC1KMT2AMEN1LMNACYP3A4 | |
| SCHEMBL13355960 | 0.78 | NPC1 (0.47) | NPC1RAB9AKMT2AMEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285587-A2 | IDENTIFICATION AND AUTHENTICATION USING LIQUID CRYSTAL MATERIAL MARKINGS | SICPA HOLDING SA (CH) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009121605-A2 | IDENTIFICATION AND AUTHENTICATION USING LIQUID CRYSTAL MATERIAL MARKINGS | SICPA HOLDING S.A. (CH) | 2009-10-08 | — | — | WO | disclosed |