SCHEMBL675482

SCHEMBL675482

OP(O)Oc1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.38
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
BCL2L1 Q07817 1/20 0.38
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
BACE1 P56817 1/20 0.34
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
HRH1 P35367 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29924556 1.00 HNF4A (0.38) HNF4AALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL28420810 0.89 HNF4A (0.38) HNF4AALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL31186148 0.86 ALDH1A1 (0.33) HNF4AALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL466616 0.85 HNF4A (0.46) HNF4AALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL3119094 0.85 BACE1 (0.34) HNF4AALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL8989572 0.85 MAPK1 (0.38) HNF4AALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL4965147 0.84 SYK (0.37) ALDH1A1TDP1L3MBTL1MAPK1PDCD1
SCHEMBL8160159 0.84 TDP1 (0.44) ALDH1A1HSD17B10HPGDBCL2L1TDP1
SCHEMBL29992101 0.84 TDP1 (0.44) ALDH1A1HSD17B10HPGDBCL2L1TDP1
SCHEMBL10598569 0.83 FABP4 (0.36) FABP3FABP5CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0032681-B1 HINDERED BIS-PHENOL PHENYL PHOSPHITES AND SYNTHETIC RESIN COMPOSITIONS HAVING ENHANCED STABILITY TO HEAT AND LIGHT ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-07-22 EP claimed
US-7968632-B2 Polycarbonate resin composition and process for producing thereof MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2011-06-28 US disclosed
US-20110077330-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
EP-2301995-A1 Polycarbonate resin composition containing triazine compound and molded article using the same Fujifilm Corporation (JP) 2011-03-30 EP disclosed
EP-0542286-B1 Decolorizable toner SHOWA DENKO KK (JP) 1996-07-17 EP disclosed
US-5449583-A Boron compounds SHOWA DENKO, K.K. (JP) 1995-09-12 US disclosed
US-5362592-A Resin binder of specified melt viscosity, near infrared ray absorbing dye, decolorizing agent, light fastness stabilizer SHOWA DENKO K.K. (JP) 1994-11-08 US disclosed
EP-0542286-A1 Decolorizable toner SHOWA DENKO KABUSHIKIKAISHA (JP) 1993-05-19 EP disclosed
US-4910238-A Photostable polyvinyl chloride ADEKA ARGUS CHEMICAL CO. LTD. (JP) 1990-03-20 US disclosed