SCHEMBL67558

SCHEMBL67558

O=S(=O)(Cl)c1ccc(Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
CYP3A4 P08684 1/20 0.65
MAPK1 P28482 1/20 0.65
CA1 P00915 4/20 0.59
CA2 P00918 4/20 0.59
CA12 O43570 3/20 0.59
CA3 P07451 3/20 0.59
CA4 P22748 3/20 0.59
CA6 P23280 3/20 0.59
CA5A P35218 3/20 0.59
CA7 P43166 3/20 0.59
CA9 Q16790 3/20 0.59
CA13 Q8N1Q1 3/20 0.59
CA14 Q9ULX7 3/20 0.59
CA5B Q9Y2D0 3/20 0.59
HSD17B10 Q99714 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
MMP2 P08253 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995084 0.92 ALDH1A1 (0.56) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL8589523 0.88 ALDH1A1 (0.52) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL651902 0.87 ALDH1A1 (0.71) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL1133769 0.86 PGR (0.53) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL5564527 0.82 ALDH1A1 (0.52) ALDH1A1CYP3A4MAPK1HSD17B10TDP1
SCHEMBL8666010 0.82 ALDH1A1 (0.57) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL9822755 0.82 ALDH1A1 (0.52) ALDH1A1CYP3A4MAPK1CA1CA2
Chlorobenzene SCHEMBL7157332 0.81 ALDH1A1 (0.80) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL9822519 0.81 CA2 (0.47) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL8124976 0.81 MMP1 (0.49) ALDH1A1CYP3A4MAPK1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5053 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865932-B Preparation method of benzothiophene sulfone compound with medicinal and fluorescent activity BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2026-05-26 CN claimed
EP-4644366-A1 PREPARATION METHODS FOR PILOCARPINE AND INTERMEDIATE COMPOUND THEREOF Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) 2025-11-05 EP claimed
CN-119735558-A Preparation method and intermediate of aza-quinolinone derivative 成都苑东生物制药股份有限公司 2025-04-01 CN claimed
CN-119708008-A Preparation method of Marbalol Sha Wei intermediate 山东科新药业有限公司 2025-03-28 CN claimed
CN-119490439-A Preparation method of arylsulfonyl amino quaternary ammonium salt antibacterial agent 苏州华道生物药业股份有限公司 2025-02-21 CN claimed
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
CN-116199607-B Preparation method of pilocarpine and intermediate compound thereof 浙江奥翔药业股份有限公司 2025-02-14 CN claimed
CN-119143705-A Benzofuran lymph specific tyrosine phosphatase inhibitor and preparation method and application thereof 山东大学 2024-12-17 CN claimed
CN-118955593-A Preparation method of 2' -alkoxy adenosine analogue 杭州中美华东制药有限公司 2024-11-15 CN claimed
EP-3247703-B1 IMPROVED PROCESS FOR PREPARING STATIN PRECURSOR CENTRIENT PHARMACEUTICALS NETHERLANDS B V (NL) 2024-10-16 EP claimed
US-4683323-A HYDROLYSIS OF SULFONIC ACID ESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-07-28 US claimed
EP-0177256-A2 Process for preparing 5,6-dialkoxy-4-alkyl-2(1h)-quinazolinones ORTHO PHARMACEUTICAL CORPORATION (US) 1986-04-09 EP claimed
EP-0082523-B1 INTERMEDIATES FOR THE PREPARATION OF 4-PHENYL-1,3-BENZODIAZEPINS AND METHODS FOR PREPARING THE INTERMEDIATES HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1986-04-02 EP claimed
EP-0115328-B1 PROCESS FOR THE PREPARATION OF 4-CHLORO-PHENYL-SULPHONYL-COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1986-02-19 EP claimed
EP-0170506-A2 Method for inversion of optically active 4-hydroxy-2-cyclopentenones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-02-05 EP claimed
US-4482742-A CATALYTIC REDUCING AND DEHALOGENATION 3,3*-DINTITRODIPHENYLSULFONE MITSUI TOATSU CHEMICALS INC. (JP) 1984-11-13 US claimed
US-4427449-A FROM LIGNOSULFONATES AND ORGANIC SULFONYL HALIDES GEORGIA-PACIFIC CORPORATION (US) 1984-01-24 US claimed
EP-0082523-A2 Intermediates for the preparation of 4-phenyl-1,3-benzodiazepins and methods for preparing the intermediates HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1983-06-29 EP claimed
US-4303776-A Bis(4-hydroxyphenyl sulfonylphenyl) bisphenyl disulfones and useful resins based thereon MOBAY CHEMICAL CORPORATION (US) 1981-12-01 US claimed
EP-0010595-A1 Bis(4-hydroxyphenylthiophenyl)biphenyldisulphones and bis(4-hydroxyphenyl-sulphonylphenyl)-biphenyldisulphones, their preparation and their use Mobay Chemical Corporation (US) 1980-05-14 EP claimed