SCHEMBL675673

SCHEMBL675673

C=CCc1cccc([Si](OC)(OC)OC)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
PPARG P37231 2/20 0.46
PPARD Q03181 2/20 0.46
PPARA Q07869 1/20 0.46
CYP3A4 P08684 5/20 0.42
ALOX5 P09917 3/20 0.42
PTGS1 P23219 2/20 0.42
AR P10275 1/20 0.42
TRPM8 Q7Z2W7 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
TP53 P04637 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
ALOX12 P18054 1/20 0.42
GABRA1 P14867 4/20 0.39
GABRB2 P47870 4/20 0.39
MAPT P10636 5/20 0.39
GAA P10253 3/20 0.39
LMNA P02545 3/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13169386 0.80 ALDH1A1 (0.42) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL436340 0.78 ALDH1A1 (0.57) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL3106769 0.78 TP53 (0.39) ALDH1A1SMN1; SMN2TP53MAPTLMNA
SCHEMBL10413593 0.77 ALDH1A1 (0.40) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL13169391 0.77 CYP3A4 (0.42) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL9812185 0.77 ALDH1A1 (0.40) ALDH1A1PPARGPPARDPPARACYP3A4
SCHEMBL19484773 0.77 IDO1 (0.33)
SCHEMBL27608831 0.77 LOXL2 (0.46) ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL3861937 0.77 TSHR (0.42) ALDH1A1SMN1; SMN2TSHRHTT
SCHEMBL1223918 0.75 TAAR1 (0.37) ALDH1A1SMN1; SMN2GABRA1GABRB2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8217388-B2 Curable organopolysiloxane composition and semiconductor device DOW CORNING TORAY COMPANY, LTD. (JP) 2012-07-10 US disclosed
US-8063143-B2 Curable organopolysiloxane composition, method of curing thereof, semiconductor device, and adhesion promotor DOW CORNING TORAY CO., LTD. (JP) 2011-11-22 US disclosed
US-20110071266-A1 Curable Organopolysiloxane Composition, Method of Curing Thereof, Semiconductor Device, And Adhesion Promotor DOW CORNING TORAY CO., LTD. (JP) 2011-03-24 US disclosed
US-20100301377-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE DOW TORAY CO., LTD. (JP) 2010-12-02 US disclosed
US-7842755-B2 Dimethylvinylsilanol-endcapped polymethylphenylsiloxane, an organohydrogenpolysiloxane, a copolymer of a vinyl monomer and a vinyl monomer with hydrosilyl groups, platinum catalyst; two-stage thermal curing; high refractive index, light transmittance, adhesion, especially to thermoplastic resins DOW CORNING TORAY COMPANY, LTD. (JP) 2010-11-30 US disclosed
EP-2061840-B1 CURABLE ORGNOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE DOW CORNING TORAY CO LTD (JP) 2010-01-06 EP disclosed
EP-2061840-A1 CURABLE ORGNOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2009-05-27 EP disclosed
US-20080262158-A1 Dimethylvinylsilanol-endcapped polymethylphenylsiloxane, an organohydrogenpolysiloxane, a copolymer of a vinyl monomer and a vinyl monomer with hydrosilyl groups, platinum catalyst; two-stage thermal curing; high refractive index, light transmittance, adhesion, especially to thermoplastic resins DOW CORNING TORAY CO., LTD. (JP) 2008-10-23 US disclosed
EP-1781741-B1 CURABLE ORGANOPOLYSILOXANE COMPOSITION, METHOD OF CURING THEREOF, SEMICONDUCTOR DEVICE, AND ADHESION PROMOTER DOW CORNING TORAY CO LTD (JP) 2008-08-27 EP disclosed
WO-2008023537-A1 CURABLE ORGNOPOLYSILOXANE COMPOSITION AND SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD (JP) 2008-02-28 WO disclosed