Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.86 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.86 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.86 |
| ▸ | PDE5A | O76074 | 1/20 | 0.86 |
| ▸ | CA1 | P00915 | 1/20 | 0.86 |
| ▸ | CA2 | P00918 | 1/20 | 0.86 |
| ▸ | HMGCR | P04035 | 1/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.86 |
| ▸ | LCK | P06239 | 1/20 | 0.86 |
| ▸ | FYN | P06241 | 1/20 | 0.86 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.86 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.86 |
| ▸ | CA6 | P23280 | 1/20 | 0.86 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.86 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.86 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.86 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.86 |
| ▸ | TST | Q16762 | 1/20 | 0.86 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.86 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentagalloyl Glucose SCHEMBL17019593 | 1.00 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Pentagalloyl Glucose SCHEMBL3147610 | 1.00 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Pentagalloyl Glucose SCHEMBL13286947 | 1.00 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Pentagalloyl Glucose SCHEMBL12129801 | 1.00 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Pentagalloyl Glucose SCHEMBL2787135 | 1.00 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Pentagalloyl Glucose SCHEMBL23484369 | 1.00 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Pentagalloyl Glucose SCHEMBL14257930 | 1.00 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Pentagalloyl Glucose SCHEMBL640108 | 1.00 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Pentagalloyl Glucose SCHEMBL14266926 | 1.00 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 | |
| Pentagalloyl Glucose SCHEMBL2789358 | 1.00 | USP2 (0.86) | USP2MAPK1TMPRSS2PDE5ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110448563-A | Application of 1,2,3,4, the 6- Penta-O-galloyl-D-glucopyranose in preparation prevention and treatment osteoporosis drug | UNIV NANJING CHINESE MEDICINE | 2019-11-15 | — | — | CN | claimed |
| CN-110384827-A | The processing method of biological tissue | 百多力股份公司 | 2019-10-29 | — | — | CN | claimed |
| CN-110272459-A | Two kinds of noval chemical compounds and its antioxidant activity position in root of Paeonia sinjiangensis | 中国药科大学 | 2019-09-24 | — | — | CN | claimed |
| CN-109632991-A | A method of utilizing HPLC characteristic spectrum detection and identification Radix Paeoniae Alba and stir-baked RADIX PAEONIAE ALBA with vino | 广东方制药有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-109490437-A | The fingerprint atlas detection method of Radix Paeoniae Alba | 南京海昌中药集团有限公司 | 2019-03-19 | — | — | CN | claimed |
| CN-106699819-B | The preparation method of Penta-O-galloyl-D-glucopyranose chemical reference substance | 泸州飞翔医药科技有限公司 | 2019-03-05 | — | — | CN | claimed |
| CN-109125333-A | Penta-O-galloyl-D-glucopyranose and 5 FU 5 fluorouracil are combined inhibiting effect and its application to HepG2 cancer cell invasion phenotype | 内蒙古大学 | 2019-01-04 | — | — | CN | claimed |
| CN-108760948-A | A kind of preparation method of 1,2,3,4,6-O- Penta-O-galloyl-D-glucopyranoses standard sample | 中国林业科学研究院林产化学工业研究所 | 2018-11-06 | — | — | CN | claimed |
| CN-108635588-A | The noble metal nano particles and its preparation method and application of Medicine small molecule modification | 国家纳米科学中心 | 2018-10-12 | — | — | CN | claimed |
| CN-108246214-A | The method that one step absorption method prepares polypeptide microcapsule | 温州生物材料与工程研究所 | 2018-07-06 | — | — | CN | claimed |
| US-20120321566-A1 | INHIBITION OF BIOFILM FORMATION BY 1,2,3,4,6-PENTA-O-GALLOYL-D-GLUCOPYRANOSE | CHANG GUNG UNIVERSITY (TW) | 2012-12-20 | — | — | US | claimed |
| EP-2462944-A2 | Methods and compositions for prevention and treatment of diabetic and aged skin | HealOr Ltd. (IL) | 2012-06-13 | — | — | EP | claimed |
| EP-2452691-A2 | Methods and compositions for prevention of diabetic and aged skin | HealOr Ltd. (IL) | 2012-05-16 | — | — | EP | claimed |
| EP-2452686-A2 | Methods and compositions for prevention and treatment of diabetic and aged skin | HealOr Ltd. (IL) | 2012-05-16 | — | — | EP | claimed |
| EP-2452687-A2 | Methods and compositions for prevention and treatment of diabetic and aged skin | HealOr Ltd. (IL) | 2012-05-16 | — | — | EP | claimed |
| US-20090203150-A1 | METHODS AND SYSTEMS FOR IDENTIFYING INSULIN MIMETICS | OHIO UNIVERSITY (US) | 2009-08-13 | — | — | US | claimed |
| EP-1940440-A2 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF DIABETIC AND AGED SKIN | Healor Ltd. (IL) | 2008-07-09 | — | — | EP | claimed |
| WO-2007026356-A2 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF DIABETIC AND AGED SKIN | HEALOR LTD. (IL) | 2007-03-08 | — | — | WO | claimed |
| WO-2007028126-A2 | METHODS AND SYSTEMS FOR IDENTIFYING INSULIN MIMETICS | OHIO UNIVERSITY (US) | 2007-03-08 | — | — | WO | claimed |
| US-20030078212-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | GUILFORD PHARMACEUTICALS INC. | 2003-04-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120321566-A1 | INHIBITION OF BIOFILM FORMATION BY 1,2,3,4,6-PENTA-O-GALLOYL-D-GLUCOPYRANOSE | PGLS, UGGT1, FUT6 | USP2 2164/4885MAPK1 847/4885TMPRSS2 2552/4885 |
| US-20030078212-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING POLY(ADP-RIBOSE) GLYCOHYDROLASE INHIBITORS AND METHODS OF USING THE SAME | PARP10, PARG, DERA | USP2 4675/4885MAPK1 2656/4885TMPRSS2 1456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.