Pentagalloyl Glucose

Pentagalloyl Glucose

SCHEMBL640108

O=C(OC[C@H]1O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H]1OC(=O)c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.86
MAPK1 P28482 2/20 0.86
TMPRSS2 O15393 1/20 0.86
PDE5A O76074 1/20 0.86
CA1 P00915 1/20 0.86
CA2 P00918 1/20 0.86
HMGCR P04035 1/20 0.86
CYP1A2 P05177 1/20 0.86
LCK P06239 1/20 0.86
FYN P06241 1/20 0.86
HSPD1 P10809 1/20 0.86
CYP2C9 P11712 1/20 0.86
CA6 P23280 1/20 0.86
TBXAS1 P24557 1/20 0.86
MAPK3 P27361 1/20 0.86
HSPE1 P61604 1/20 0.86
MAPK14 Q16539 1/20 0.86
TST Q16762 1/20 0.86
SLCO1B3 Q9NPD5 1/20 0.86
L3MBTL1 Q9Y468 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentagalloyl Glucose SCHEMBL17019593 1.00 USP2 (0.86) USP2MAPK1TMPRSS2PDE5ACA1
Pentagalloyl Glucose SCHEMBL3147610 1.00 USP2 (0.86) USP2MAPK1TMPRSS2PDE5ACA1
Pentagalloyl Glucose SCHEMBL13286947 1.00 USP2 (0.86) USP2MAPK1TMPRSS2PDE5ACA1
Pentagalloyl Glucose SCHEMBL12129801 1.00 USP2 (0.86) USP2MAPK1TMPRSS2PDE5ACA1
Pentagalloyl Glucose SCHEMBL2787135 1.00 USP2 (0.86) USP2MAPK1TMPRSS2PDE5ACA1
Pentagalloyl Glucose SCHEMBL675693 1.00 USP2 (0.86) USP2MAPK1TMPRSS2PDE5ACA1
Pentagalloyl Glucose SCHEMBL23484369 1.00 USP2 (0.86) USP2MAPK1TMPRSS2PDE5ACA1
Pentagalloyl Glucose SCHEMBL14257930 1.00 USP2 (0.86) USP2MAPK1TMPRSS2PDE5ACA1
Pentagalloyl Glucose SCHEMBL14266926 1.00 USP2 (0.86) USP2MAPK1TMPRSS2PDE5ACA1
Pentagalloyl Glucose SCHEMBL2789358 1.00 USP2 (0.86) USP2MAPK1TMPRSS2PDE5ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636145-B2 Method for the production of crosslinked and optionally shaped tissue with selective adjustment of thickness, shape and/or flexibility BIOTRONIK AG (CH) 2026-05-26 US claimed
CN-122017088-A UPLC-based construction method of characteristic spectrum of xipayi Gum fixing liquid and method for measuring content of characteristic components of UPLC-based construction method 新奇康药业股份有限公司 2026-05-12 CN claimed
US-20260069621-A1 Pentagalloyl glucose (PGG) for use in treatment of pulmonary hypertension UNIV BERLIN CHARITE (DE) 2026-03-12 US claimed
US-12303134-B2 Systems for aneurysm treatment Nectero Medical, Inc (US) 2025-05-20 US claimed
CN-119970765-A Pharmaceutical composition for synergistic treatment of thrombosis and application thereof 南京中医药大学 2025-05-13 CN claimed
CN-116270691-B Pharmaceutical composition 中国医学科学院药用植物研究所 2025-05-09 CN claimed
WO-2025049966-A9 METHODS AND COMPOSITIONS FOR INCREASING ROR1 EXPRESSION INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER (US) 2025-04-17 WO claimed
CN-119564612-A Preparation method of pentagalloyl glucose liposome, and product and application thereof 上海玮沐医疗科技有限公司 2025-03-07 CN claimed
WO-2025049966-A2 METHODS AND COMPOSITIONS FOR INCREASING ROR1 EXPRESSION WASIK MARIUSZ A (US) 2025-03-06 WO claimed
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same SYMRISE AG (DE) 2025-02-27 US claimed
WO-2009158487-A2 TREATMENT OF NEPHROLITHIASIS AND UROLITHIASIS USING 1,2,3,4,6-PENTA-O-GALLOYL-BETA-D-GLUCOSE (PGG) MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2009-12-30 WO claimed
US-20090170788-A1 NOVEL USE OF 1, 2, 3, 4, 6-PENTA-O-GALLOYL-BETA-D-GLUCOSE KIM, TAE-YOON (KR) 2009-07-02 US claimed
WO-2007081190-A1 NOVEL USE OF 1,2,3,4,6-PENTA-O-GALLOYL-BETA-D-GLUCOSE BIO CLUE & SOLUTION CO., LTD. (KR) 2007-07-19 WO claimed
US-20070148185-A1 Novel therapeutic target for protozoal diseases VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2007-06-28 US claimed
WO-2007047579-A2 A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2007-04-26 WO claimed
EP-1545554-A4 METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS UNIV OHIO (US) 2006-06-14 EP claimed
US-20060058243-A1 Methods and compositions for treating diabetes mellitis OHIO UNIVERSITY 2006-03-16 US claimed
EP-1545554-A1 METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS Ohio University (US) 2005-06-29 EP claimed
US-20040247698-A1 Erectile Dysfunction Treatment VALENZUELA CORTES CARMEN MARIA (CL) 2004-12-09 US claimed
WO-2004009094-A1 METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS OHIO UNIVERSITY (US) 2004-01-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636145-B2 Method for the production of crosslinked and optionally shaped tissue with selective adjustment of thickness, shape and/or flexibility PGF, MMP1, CTCF USP2 1814/4885MAPK1 4726/4885TMPRSS2 1468/4885
US-20260069621-A1 Pentagalloyl glucose (PGG) for use in treatment of pulmonary hypertension SLC5A2, SLC2A2, SLC2A1 USP2 858/4885MAPK1 797/4885TMPRSS2 1383/4885
US-20060058243-A1 Methods and compositions for treating diabetes mellitis IAPP, GCG, MTPN USP2 4592/4885MAPK1 1019/4885TMPRSS2 3455/4885
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same TAS2R5, TAS2R7, TAS2R8 USP2 4458/4885MAPK1 3379/4885TMPRSS2 3144/4885
US-20040247698-A1 Erectile Dysfunction Treatment PDE3A, PDE3B, PDE12 USP2 2078/4885MAPK1 2445/4885TMPRSS2 2417/4885
US-20090170788-A1 NOVEL USE OF 1, 2, 3, 4, 6-PENTA-O-GALLOYL-BETA-D-GLUCOSE UGGT1, G6PD, HK1 USP2 2319/4885MAPK1 286/4885TMPRSS2 3762/4885
US-12303134-B2 Systems for aneurysm treatment PLG, GANAB, PGD USP2 671/4885MAPK1 1209/4885TMPRSS2 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.