Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16756501 | 0.83 | ALPL (0.58) | TAAR1MLKLKMT2AMAPK1TP53 | |
| SCHEMBL3397595 | 0.83 | ALPL (0.58) | TAAR1MLKLKMT2AMAPK1TP53 | |
| SCHEMBL16756243 | 0.83 | ALPL (0.58) | TAAR1MLKLKMT2AMAPK1TP53 | |
| SCHEMBL16147270 | 0.80 | NPC1 (0.53) | TAAR1MLKLKMT2AMAPK1TP53 | |
| SCHEMBL2147079 | 0.79 | ALDH1A1 (0.66) | TAAR1MLKLKMT2AMAPK1MEN1 | |
| SCHEMBL14770674 | 0.78 | SMN1; SMN2 (0.56) | TAAR1MLKLKMT2AMEN1IDO1 | |
| SCHEMBL29212596 | 0.77 | MLKL (0.58) | TAAR1MLKLKMT2AMAPK1MEN1 | |
| SCHEMBL8594223 | 0.74 | MLKL (0.50) | TAAR1MLKLKMT2AMAPK1MEN1 | |
| SCHEMBL30665026 | 0.72 | ALDH1A1 (0.66) | TAAR1MLKLKMT2AMAPK1TP53 | |
| SCHEMBL85832 | 0.72 | ALDH1A1 (0.66) | TAAR1MLKLKMT2AMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |