Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14770686 | 0.86 | MLKL (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL14770549 | 0.85 | ALDH1A1 (0.42) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL16148339 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL16756243 | 0.84 | ALPL (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL3397595 | 0.84 | ALPL (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL16756501 | 0.84 | ALPL (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL14770661 | 0.84 | MLKL (0.72) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL17910926 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL14770550 | 0.81 | FLT3 (0.40) | KDM4EMLKLMEN1KMT2APOLB | |
| SCHEMBL14770492 | 0.81 | AMY1A (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096531-B2 | Fused imidazole derivative | TOA EIYO LTD. (JP) | 2015-08-04 | — | — | US | disclosed |
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA EIYO LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | CACNA1E, CACNA1G, CACNA1A | SMN1; SMN2 1964/4885NPC1 2440/4885RAB9A 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.