SCHEMBL6757705

SCHEMBL6757705

CC(C)Oc1cn(Cc2ccccc2)c(=O)o1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
P2RX7 Q99572 4/20 0.40
P2RX3 P56373 1/20 0.39
MIF P14174 3/20 0.38
BRD4 O60885 2/20 0.38
MAPT P10636 1/20 0.38
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36
CYP2D6 P10635 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
BRD2 P25440 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4680991 0.83 HPGD (0.49) HPGDMEN1KMT2AP2RX7MIF
SCHEMBL6759650 0.81 HPGD (0.47) HPGDMEN1KMT2AP2RX7MIF
SCHEMBL6764108 0.79 MEN1 (0.48) HPGDMEN1KMT2AP2RX7MIF
SCHEMBL6757710 0.79 MAPK14 (0.49) HPGDMEN1KMT2AMIFHTT
SCHEMBL6761320 0.78 HPGD (0.44) HPGDMEN1KMT2ABRD4TP53
SCHEMBL6764255 0.77 TP53 (0.45) HPGDMEN1KMT2APDE4APDE4B
SCHEMBL22252624 0.74 HPGD (0.49) HPGDMEN1KMT2AMIFBRD4
SCHEMBL6760106 0.72 CYP1A2 (0.47) HPGDMEN1KMT2AMAPTKDM4E
SCHEMBL4678109 0.72 FAAH (0.43) HPGDMEN1KMT2ACYP2D6
SCHEMBL4678103 0.72 FAAH (0.43) HPGDMEN1KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723860-B2 7a-alkoxy-4H-pyrano[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1207162-B1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES (JP) 2004-02-25 EP disclosed
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2002-06-13 US disclosed
EP-1207162-A1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same Ube Industries, Ltd. (JP) 2002-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same ACSL1, ACSL4, ACSL3 HPGD 1274/4885MEN1 4677/4885KMT2A 3421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.