Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6761940 | 0.85 | LMNA (0.42) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6762839 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL26705914 | 0.81 | PTGS2 (0.49) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL25613450 | 0.81 | PTGS2 (0.49) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7108430 | 0.81 | GCGR (0.41) | LMNAMAPTL3MBTL1KDM4EHTT | |
| SCHEMBL6765106 | 0.81 | HSD11B1 (0.38) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6761314 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6757922 | 0.77 | CYP2D6 (0.46) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6757914 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6760296 | 0.75 | LMNA (0.36) | SMN1; SMN2LMNAALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072720-B2 | Aqueous ink, ink cartridge and ink jet recording method | CANON KABUSHIKI KAISHA (JP) | 2021-07-27 | — | — | US | disclosed |
| US-20200071554-A1 | AQUEOUS INK, INK CARTRIDGE AND INK JET RECORDING METHOD | CANON KABUSHIKI KAISHA (JP) | 2020-03-05 | — | — | US | disclosed |
| US-6723483-B1 | Sulfonium salt compounds | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1113005-B1 | Sulfonium salt compounds | WAKO PURE CHEM IND LTD (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-1238969-A2 | Sulfonium salt compounds | Wako Pure Chemical Industries, Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-1113005-A1 | Sulfonium salt compounds | Wako Pure Chemical Industries, Ltd. (JP) | 2001-07-04 | — | — | EP | disclosed |