Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.52 |
| ▸ | GABRE | P78334 | 1/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19135786 | 0.82 | MAPT (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23191714 | 0.77 | AHR (0.71) | AHRALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL17669649 | 0.76 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6756498 | 0.76 | SIRT2 (0.39) | ALDH1A1KMT2AMEN1MAPTSIRT2 | |
| Carbazole SCHEMBL27971512 | 0.75 | ALDH1A1 (0.70) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31378801 | 0.75 | DAO (0.58) | CTSVCTSLALDH1A1KMT2AMEN1 | |
| SCHEMBL30272742 | 0.73 | CTSV (0.79) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30272743 | 0.73 | CTSV (0.79) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL151534 | 0.73 | CTSV (0.79) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30272741 | 0.73 | CTSV (0.79) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713473-B1 | 6-CARBAMATE-1,2,3,4-TETRAHYDROCARBAZOLE DERIVATIVES; AFFINITY FOR NEUROPEPTIDE Y RECEPTORS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1184373-A1 | TRICYCLIC COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-03-06 | — | — | EP | disclosed |