Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757995 | 0.76 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL17669631 | 0.74 | AHR (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12920718 | 0.73 | CASP6 (0.47) | KMT2AMEN1MAPTRAB9AALDH1A1 | |
| SCHEMBL12845091 | 0.70 | MAPT (0.51) | AHRKMT2AMEN1MAPTRAB9A | |
| SCHEMBL30305750 | 0.70 | MAPT (0.51) | AHRKMT2AMEN1MAPTRAB9A | |
| SCHEMBL26656750 | 0.70 | CTSB (0.56) | KMT2AMEN1MAPTRAB9AKDM4E | |
| SCHEMBL26656753 | 0.70 | CTSB (0.56) | KMT2AMEN1MAPTRAB9AKDM4E | |
| SCHEMBL26656751 | 0.70 | CTSB (0.56) | KMT2AMEN1MAPTRAB9AKDM4E | |
| Carbazole SCHEMBL28988608 | 0.70 | ALDH1A1 (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Carbazole SCHEMBL27971512 | 0.70 | ALDH1A1 (0.70) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005730-B2 | 3-aminocarbazole compound, pharmaceutical composition containing it and preparation method therefor | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2018-06-26 | — | — | US | disclosed |
| US-20160102056-A1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005730-B2 | 3-aminocarbazole compound, pharmaceutical composition containing it and preparation method therefor | PTGES3, PTGER3, PTGES | GABRP 210/4885GABRD 74/4885GABRA1 105/4885 |
| US-20160102056-A1 | 3-AMINOCARBAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING IT AND PREPARATION METHOD THEREFOR | PTGES3, PTGER3, PTGES | GABRP 210/4885GABRD 74/4885GABRA1 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.