SCHEMBL6758045

SCHEMBL6758045

CC(O)COC(=O)CCC1CN1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.49
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
ATM Q13315 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6129181 0.78 ALDH1A1 (0.44) MAPTLMNAKDM4EMEN1KMT2A
SCHEMBL8537018 0.77 DGKA (0.38) MAPTTDP1
SCHEMBL822396 0.77 MAPT (0.67) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL15302354 0.74
SCHEMBL822246 0.73 MAPT (0.74) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL821850 0.73 MAPT (0.81) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL6758044 0.73 MAPT (0.37) MAPTTSHR
SCHEMBL821851 0.71 MAPT (0.85) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL822254 0.71 MAPT (0.85) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL821856 0.71 MAPT (0.85) MAPTLMNAKDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6716909-B2 FORMED BY EMULSION POLYMERIZATION; CLEAR COATING; SMOOTHNESS; FOR APPLICATION TO AUTOMOTIVE BODIES NIPPON PAINT CO., LTD. (JP) 2004-04-06 US disclosed
US-20020077410-A1 Water-borne coating composition and method of forming multilayer coating film NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2002-06-20 US disclosed