SCHEMBL675838

SCHEMBL675838

C=CC[SiH](OC)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.33
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL135716 0.81 MEN1 (0.32) MEN1KMT2A
SCHEMBL22654156 0.80 CA2 (0.34) TSHRMEN1KMT2A
SCHEMBL252065 0.80 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL9900069 0.78
SCHEMBL14956287 0.78 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL22654249 0.78 KDM4E (0.37) ALDH1A1SMN1; SMN2
SCHEMBL18950137 0.76 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL18145380 0.74
SCHEMBL6268335 0.74 CA4 (0.35) ALDH1A1TP53CA4
SCHEMBL580082 0.72 ALDH1A1 (0.33) ALDH1A1TSHRCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1746132-B1 SILICON-CONTAINING CURABLE COMPOSITION AND CURED OBJECT OBTAINED BY THERMALLY CURING THE SAME ADEKA CORP (JP) 2013-07-10 EP disclosed
EP-1801871-B1 SEMICONDUCTOR DEVICE KANSAI ELECTRIC POWER CO (JP) 2012-07-11 EP disclosed
US-7939614-B2 Silicon-containing curing composition and heat cured product thereof ADEKA CORPORATION (JP) 2011-05-10 US disclosed
US-7772594-B2 covered with a synthetic high molecular compound which is a silicon-containing curable polymer composition having excellent heat resistance and flexibility; high voltage; fluorine-free; platinum curing catalyst THE KANSAI ELECTRIC POWER CO., INC. (JP) 2010-08-10 US disclosed
US-20080210948-A1 High-Heat-Resistive Semiconductor Device THE KANSAI ELECTRIC POWER CO., INC. (JP) 2008-09-04 US disclosed
US-20070197755-A1 Silicon-containing curing composition and heat cured product thereof ADEKA CORPORATION (JP) 2007-08-23 US disclosed
EP-1801871-A1 SEMICONDUCTOR DEVICE THE KANSAI ELECTRIC POWER CO., INC. (JP) 2007-06-27 EP disclosed
EP-1746132-A1 SILICON-CONTAINING CURABLE COMPOSITION AND CURED OBJECT OBTAINED BY THERMALLY CURING THE SAME Adeka Corporation (JP) 2007-01-24 EP disclosed