SCHEMBL135716

SCHEMBL135716

C=CC[SiH](OCC)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22654210 0.82 SMN1; SMN2 (0.33)
SCHEMBL675838 0.81 ACHE (0.33) MEN1KMT2A
SCHEMBL22654156 0.81 CA2 (0.34) MEN1KMT2A
SCHEMBL22654249 0.78 KDM4E (0.37)
SCHEMBL705286 0.78 LTA4H (0.34) RELA
SCHEMBL674277 0.77 RELA (0.32) MEN1KMT2ARELA
SCHEMBL252065 0.77 ALDH1A1 (0.30)
SCHEMBL9900069 0.76
SCHEMBL23701265 0.75 LTA4H (0.32)
SCHEMBL708782 0.75 TP53 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2665777-B1 HYDROLYSIS-STABLE POLYAMIDES BASF SE (DE) 2014-11-19 EP disclosed
US-8623983-B2 Terpolymer of electron-deficient olefins, olefins without electron-withdrawing substituents, and alkoxyvinylsilanes BASF SE (DE) 2014-01-07 US disclosed
EP-2614092-A1 TERPOLYMER FORMED FROM ELECTRON-DEFICIENT OLEFINS, OLEFINS WITHOUT ELECTRON-WITHDRAWING SUBSTITUENTS AND ALKOXYVINYLSILANES BASF SE (DE) 2013-07-17 EP disclosed
EP-1746132-B1 SILICON-CONTAINING CURABLE COMPOSITION AND CURED OBJECT OBTAINED BY THERMALLY CURING THE SAME ADEKA CORP (JP) 2013-07-10 EP disclosed
US-20120184664-A1 HYDROLYSIS-RESISTANT POLYAMIDES BASF SE (DE) 2012-07-19 US disclosed
EP-1801871-B1 SEMICONDUCTOR DEVICE KANSAI ELECTRIC POWER CO (JP) 2012-07-11 EP disclosed
WO-2012032005-A1 TERPOLYMER FORMED FROM ELECTRON-DEFICIENT OLEFINS, OLEFINS WITHOUT ELECTRON-WITHDRAWING SUBSTITUENTS AND ALKOXYVINYLSILANES BASF SE (DE) 2012-03-15 WO disclosed
US-20120059101-A1 TERPOLYMER OF ELECTRON-DEFICIENT OLEFINS, OLEFINS WITHOUT ELECTRON-WITHDRAWING SUBSTITUENTS, AND ALKOXYVINYLSILANES BASF SE (DE) 2012-03-08 US disclosed
US-7939614-B2 Silicon-containing curing composition and heat cured product thereof ADEKA CORPORATION (JP) 2011-05-10 US disclosed
US-7772594-B2 covered with a synthetic high molecular compound which is a silicon-containing curable polymer composition having excellent heat resistance and flexibility; high voltage; fluorine-free; platinum curing catalyst THE KANSAI ELECTRIC POWER CO., INC. (JP) 2010-08-10 US disclosed
US-20080210948-A1 High-Heat-Resistive Semiconductor Device THE KANSAI ELECTRIC POWER CO., INC. (JP) 2008-09-04 US disclosed
US-20070197755-A1 Silicon-containing curing composition and heat cured product thereof ADEKA CORPORATION (JP) 2007-08-23 US disclosed
EP-1801871-A1 SEMICONDUCTOR DEVICE THE KANSAI ELECTRIC POWER CO., INC. (JP) 2007-06-27 EP disclosed
EP-1746132-A1 SILICON-CONTAINING CURABLE COMPOSITION AND CURED OBJECT OBTAINED BY THERMALLY CURING THE SAME Adeka Corporation (JP) 2007-01-24 EP disclosed