⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18145380 | 0.84 | — | — | |
| SCHEMBL252065 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL675838 | 0.78 | ACHE (0.33) | — | |
| SCHEMBL135716 | 0.76 | MEN1 (0.32) | — | |
| SCHEMBL18950137 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL22654156 | 0.72 | CA2 (0.34) | — | |
| SCHEMBL216362 | 0.70 | ALDH1A1 (0.36) | — | |
| SCHEMBL860549 | 0.70 | CYP2C19 (0.36) | — | |
| SCHEMBL22654249 | 0.69 | KDM4E (0.37) | — | |
| SCHEMBL22654210 | 0.67 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649113-A1 | SILOXANE COMPOSITIONS INCLUDING METAL-OXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS | Dow Corning Corporation (US) | 2013-10-16 | — | — | EP | disclosed |
| EP-2649131-A1 | SILOXANE COMPOSITIONS INCLUDING TITANIUM DIOXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS | Dow Corning Corporation (US) | 2013-10-16 | — | — | EP | disclosed |
| EP-2649114-A1 | SILOXANE COMPOSITIONS SUITABLE FOR FORMING ENCAPSULANTS | Dow Corning Corporation (US) | 2013-10-16 | — | — | EP | disclosed |
| US-20130256742-A1 | Siloxane-Compositions Including Metal-Oxide Nanoparticles Suitable For Forming Encapsulants | DOW CORNING CORPORATION (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130256741-A1 | Siloxane Compositions Suitable For Forming Encapsulants | DOW CORNING CORPORATION | 2013-10-03 | — | — | US | disclosed |
| WO-2012078582-A1 | SILOXANE COMPOSITIONS INCLUDING METAL-OXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS | DOW CORNING CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012078617-A1 | SILOXANE COMPOSITIONS INCLUDING TITANIUM DIOXIDE NANOPARTICLES SUITABLE FOR FORMING ENCAPSULANTS | DOW CORNING CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012078594-A1 | SILOXANE COMPOSITIONS SUITABLE FOR FORMING ENCAPSULANTS | DOW CORNING CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |