Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 7/20 | 0.98 |
| ▸ | GAA | P10253 | 7/20 | 0.98 |
| ▸ | SI | P14410 | 7/20 | 0.98 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.98 |
| ▸ | FASN | P49327 | 5/20 | 0.98 |
| ▸ | IDH1 | O75874 | 4/20 | 0.98 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.98 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.98 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.98 |
| ▸ | RELA | Q04206 | 3/20 | 0.98 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.98 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.98 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.98 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.98 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.98 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.98 |
| ▸ | MAPT | P10636 | 2/20 | 0.98 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.98 |
| ▸ | MEN1 | O00255 | 1/20 | 0.98 |
| ▸ | KDM1A | O60341 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mangostin SCHEMBL354735 | 0.99 | MGAM (1.00) | MGAMGAASIMGAM2FASN | |
| Mangostin SCHEMBL29466055 | 0.99 | MGAM (1.00) | MGAMGAASIMGAM2FASN | |
| Mangostin SCHEMBL29433195 | 0.99 | MGAM (1.00) | MGAMGAASIMGAM2FASN | |
| Mangostin SCHEMBL27218086 | 0.95 | MGAM (0.93) | MGAMGAASIMGAM2FASN | |
| SCHEMBL30830372 | 0.91 | MGAM (0.85) | MGAMGAASIMGAM2FASN | |
| SCHEMBL3742268 | 0.91 | MGAM (1.00) | MGAMGAASIMGAM2FASN | |
| SCHEMBL29929598 | 0.91 | MGAM (1.00) | MGAMGAASIMGAM2FASN | |
| SCHEMBL3750432 | 0.91 | MGAM (0.85) | MGAMGAASIMGAM2FASN | |
| SCHEMBL29974819 | 0.91 | MGAM (1.00) | MGAMGAASIMGAM2FASN | |
| Cowanin SCHEMBL29378034 | 0.91 | MGAM (1.00) | MGAMGAASIMGAM2FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10471114-B2 | Composition from Sphaeranthus indicus and Garcinia mangostana for the control of metabolic syndrome | LAILA NUTRACEUTICALS (IN) | 2019-11-12 | — | — | US | disclosed |
| EP-2391374-B1 | COMPOSITION FROM SPHAERANTHUS INDICUS AND GARCINIA MANGOSTANA FOR THE CONTROL OF METABOLIC SYNDROME | LAILA NUTRACEUTICALS (IN) | 2018-11-14 | — | — | EP | disclosed |
| US-20160074457-A1 | COMPOSITION FROM SPHAERANTHUS INDICUS AND GARCINIA MANGOSTANA FOR THE CONTROL OF METABOLIC SYNDROME | LAILA NUTRACEUTICALS (IN) | 2016-03-17 | — | — | US | disclosed |
| US-9241964-B2 | Composition from Sphaeranthus indicus and Garcinia mangostana for the control of metabolic syndrome | LAILA NUTRACEUTICALS (US) | 2016-01-26 | — | — | US | disclosed |
| EP-2391374-A2 | COMPOSITION FROM SPHAERANTHUS INDICUS AND GARCINIA MANGOSTANA FOR THE CONTROL OF METABOLIC SYNDROME | Laila Nutraceuticals (IN) | 2011-12-07 | — | — | EP | disclosed |
| US-20110280951-A1 | COMPOSITION FROM SPHAERANTHUS INDICUS AND GARCINIA MANGOSTANA FOR THE CONTROL OF METABOLIC SYNDROME | LAILA NUTRACEUTICALS (IN) | 2011-11-17 | — | — | US | disclosed |
| WO-2010100653-A2 | COMPOSITION FROM SPHAERANTHUS INDICUS AND GARCINIA MANGOSTANA FOR THE CONTROL OF METABOLIC SYNDROME | LAILA NUTRACEUTICALS (IN) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280951-A1 | COMPOSITION FROM SPHAERANTHUS INDICUS AND GARCINIA MANGOSTANA FOR THE CONTROL OF METABOLIC SYNDROME | GPR119, SREBF1, PNLIP | MGAM 45/4885GAA 176/4885SI 15/4885 |
| US-10471114-B2 | Composition from Sphaeranthus indicus and Garcinia mangostana for the control of metabolic syndrome | GPR119, SREBF1, PNLIP | MGAM 43/4885GAA 236/4885SI 23/4885 |
| US-20160074457-A1 | COMPOSITION FROM SPHAERANTHUS INDICUS AND GARCINIA MANGOSTANA FOR THE CONTROL OF METABOLIC SYNDROME | GPR119, SREBF1, PNLIP | MGAM 43/4885GAA 236/4885SI 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.