Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 11/20 | 0.47 |
| ▸ | GSK3B | P49841 | 9/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.39 |
| ▸ | WNT1 | P04628 | 4/20 | 0.38 |
| ▸ | TTK | P33981 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | CLK3 | P49761 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KAT7 | O95251 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756960 | 0.83 | DYRK1A (0.48) | DYRK1AGSK3BMAP4K4KAT5WNT1 | |
| SCHEMBL6760162 | 0.76 | USP2 (0.45) | DYRK1AGSK3BMAP4K4KAT5WNT1 | |
| SCHEMBL4755015 | 0.74 | KAT6A (0.39) | KAT5MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL8440378 | 0.71 | ALDH1A1 (0.60) | MEN1ALDH1A1MAPTHPGDXBP1 | |
| SCHEMBL67540 | 0.71 | ALDH1A1 (0.62) | MEN1ALDH1A1MAPTHPGDXBP1 | |
| SCHEMBL588343 | 0.71 | ALDH1A1 (0.62) | MEN1ALDH1A1MAPTHPGDXBP1 | |
| SCHEMBL6755660 | 0.70 | DYRK1A (0.38) | DYRK1AGSK3BKAT5MEN1ALDH1A1 | |
| SCHEMBL5188952 | 0.70 | KDM4E (0.64) | MEN1ALDH1A1MAPTHPGDXBP1 | |
| SCHEMBL17149168 | 0.68 | USP2 (0.46) | DYRK1AGSK3BKAT5WNT1TTK | |
| SCHEMBL30570165 | 0.68 | CNR2 (0.56) | MEN1ALDH1A1MAPTHPGDXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |