Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525098 | 1.00 | MAPK1 (0.39) | MAPK1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL232990 | 0.79 | LMNA (0.41) | MAPK1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL1387795 | 0.78 | MAPT (0.39) | MAPK1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL1389126 | 0.75 | FGFR1 (0.42) | MAPK1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL6921270 | 0.75 | MAPT (0.42) | MAPK1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL6949569 | 0.74 | CUL4A (0.45) | MAPK1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL25171318 | 0.73 | LMNA (0.54) | MAPK1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL70993 | 0.73 | LMNA (0.54) | MAPK1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL29370508 | 0.73 | LMNA (0.54) | MAPK1LMNATP53CYP1A2CYP3A4 | |
| Benzene SCHEMBL27791155 | 0.73 | LMNA (0.54) | MAPK1LMNATP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743431-B1 | 1,2-PHENYLENE BRIDGED 1-INDENYL-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERISATION | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2025-04-16 | — | — | EP | disclosed |
| US-11691998-B2 | 1,2-phenylene bridged 1-indenyl-2-indenyl metallocene complexes for olefin polymerisation | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2023-07-04 | — | — | US | disclosed |
| US-20230086874-A1 | 1,2-PHENYLENE BRIDGED 1-INDENYL-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERISATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2023-03-23 | — | — | US | disclosed |
| US-20210079032-A1 | 1,2-PHENYLENE BRIDGED 1-INDENYL-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERISATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-03-18 | — | — | US | disclosed |
| US-6723676-B2 | USE AS CATALYSTS FOR THE (CO) POLYMERIZATION OF OLEFINIC AND/OR DIOLEFINIC MONOMERS. | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |
| US-20030027954-A1 | 1,3-disubstituted indene complexes | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-06 | — | — | US | disclosed |
| EP-1264835-A1 | 1,3-disubstituted indene complexes | BAYER AG (DE) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210079032-A1 | 1,2-PHENYLENE BRIDGED 1-INDENYL-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERISATION | MT-CO1, MT-CO2, INF2 | MAPK1 1764/4885LMNA 2726/4885TP53 3609/4885 |
| US-20230086874-A1 | 1,2-PHENYLENE BRIDGED 1-INDENYL-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERISATION | MT-CO1, MT-CO2, INF2 | MAPK1 1757/4885LMNA 2720/4885TP53 3642/4885 |
| US-20030027954-A1 | 1,3-disubstituted indene complexes | ORC3, IDO1, IDH3A | MAPK1 2305/4885LMNA 4514/4885TP53 1701/4885 |
| US-11691998-B2 | 1,2-phenylene bridged 1-indenyl-2-indenyl metallocene complexes for olefin polymerisation | MT-CO1, MT-CO2, INF2 | MAPK1 1757/4885LMNA 2720/4885TP53 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.