Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223768 | 0.86 | HSD17B10 (0.52) | USP2ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL3505628 | 0.85 | MRGPRX4 (0.54) | USP2L3MBTL1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL6760076 | 0.85 | USP2 (0.54) | USP2ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL8367495 | 0.83 | L3MBTL1 (0.56) | USP2L3MBTL1ALDH1A1HPGDTP53 | |
| SCHEMBL5873911 | 0.81 | SMN1; SMN2 (0.58) | USP2L3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL6589289 | 0.80 | GAA (0.51) | USP2L3MBTL1ALDH1A1GAAKDM4E | |
| SCHEMBL6757005 | 0.80 | PYGL (0.56) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL6566669 | 0.79 | HSD17B10 (0.50) | ALDH1A1GAAKDM4EGLAHSD17B10 | |
| SCHEMBL3507291 | 0.79 | USP2 (0.61) | USP2L3MBTL1ALDH1A1GAAKDM4E | |
| SCHEMBL2436534 | 0.79 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1HPGDTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720424-B1 | VEGF (VASCULAR ENDOTHELIAL GROWTH FACTOR) RECEPTOR ANTAGONISTS AND ANGIOGENESIS INHIBITORS SUPPRESS VASCULAR HYPERPERMEABILITY; PHENYLALKYLCARBONYL SUBSTITUENT ON THE AMINO | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| EP-1193246-A1 | AMINOBENZOIC ACID DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-04-03 | — | — | EP | disclosed |